A0A812I7T9 · A0A812I7T9_9DINO
- ProteinCTP synthase
- Genepyr-7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids430 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
Catalytic activity
- ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H+ + L-glutamate + phosphate
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 272 | Nucleophile | ||||
Sequence: C | ||||||
Active site | 404 | |||||
Sequence: H | ||||||
Active site | 406 | |||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | CTP synthase activity | |
Molecular Function | identical protein binding | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | glutamine metabolic process | |
Biological Process | pyrimidine nucleobase biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCTP synthase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Sar > Alveolata > Dinophyceae > Suessiales > Symbiodiniaceae > Symbiodinium
Accessions
- Primary accessionA0A812I7T9
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-125 | CTP synthase N-terminal | ||||
Sequence: MIELGGTIGDIESMPFIEALRQLKFNLPENSLVWCHCSYIPNMSGQKTKPTQHSVKTLLGLGVQPDLIICRCPDPVLEETRKKIANQCNIPANRIISAHDVTNLFHVPGIFAQQHLIGVMNGLLK | ||||||
Domain | 180-422 | Glutamine amidotransferase | ||||
Sequence: DAYQSVLAALSHAAVAVTRKLKVDWVDATELEAPSKDSPDYEEEMKRKAAAEARLKAADGIFVPGGFGDRGVAGKTRAAGLAREWKKPYLGVCLGMQVALINFAKEVLGIPDATSEEFDTAGTSKNHVVIFMPEISKDTMGANMRLGARWVEFTKPEESLASALYGGANRVHERHRHRYEFNVAFKERMEKKGLIFSGQDESKERMDIIEMATKDHPFFMGVQYHPEYKSRPGQPSPPFFGFV |
Sequence similarities
Belongs to the CTP synthase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length430
- Mass (Da)47,635
- Last updated2021-09-29 v1
- Checksum32742084AC2F8845
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: M |
Keywords
- Technical term