A0A804MU90 · A0A804MU90_MAIZE

  • Protein
    Lon protease homolog, mitochondrial
  • Gene
    103647953
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.

Catalytic activity

  • Hydrolysis of proteins in presence of ATP.
    EC:3.4.21.53 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site, active site.

1771100200300400500600700
Type
IDPosition(s)Description
Binding site261-268ATP (UniProtKB | ChEBI)
Active site670
Active site713

GO annotations

AspectTerm
Cellular Componentmitochondrial matrix
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent peptidase activity
Molecular Functionsequence-specific DNA binding
Molecular Functionserine-type endopeptidase activity
Biological Processcellular response to oxidative stress
Biological Processchaperone-mediated protein complex assembly
Biological Processoxidation-dependent protein catabolic process
Biological Processprotein quality control for misfolded or incompletely synthesized proteins

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lon protease homolog, mitochondrial
  • EC number

Gene names

    • Name
      103647953

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • cv. B73
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea

Accessions

  • Primary accession
    A0A804MU90

Proteomes

Genome annotation databases

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer or homoheptamer. Organized in a ring with a central cavity.

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain1-106Lon N-terminal
Compositional bias512-532Polar residues
Region512-547Disordered
Compositional bias533-547Basic and acidic residues
Domain580-764Lon proteolytic

Sequence similarities

Belongs to the peptidase S16 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    771
  • Mass (Da)
    85,190
  • Last updated
    2021-09-29 v1
  • Checksum
    2FDA61E10C3F627E
MQVEEDPLTVKVDHLKEKPYNKDDDVIKATSFEVISTLREVLRTSSLWKDHVQTYTQHIGDFNYQRLADFGAAISGANKLLCQEVLEELDVYKRLKFTLELVKKEMEISKLQQSIAKAIEEKISGDQRRYLLNEQLKAIKKELGLETDDKTALSAKFRERIESKKDRCPSHVLQVIEEELTKLQLLEASSSEFSVTRNYLDWLTVLPWGNYSDENFDVHRAQKILDEDHYGLSDVKERILEFIAVGKLRGTSQGKIICLSGPPGVGKTSIGRSIARALNRQFYRFSVGGLADVAEIKGHRRTYVGAMPGKMVQCLKSVGTANPLVLIDEIDKLGKGHSGDPASALLELLDPEQNVNFLDHYLDVPIDLSKVLFVCTANVIETIPNPLLDRMEIIAIAGYITDEKMHIARDYLEKNTRQACGIKPEQVEVTDAALLALIENYCREAGVRNLQKHIEKIYRKIALQLVRQGVSNEPDQESLGVTVNEESNSGDSITAKDEIVKDPAVEDASVANNVTNPASEEANEVNLTTEAPKEDSTSKKTDGVAEDAADKATEKVVVDSSNLGDFVGKPVFQAERIYEQTPVGVVMGLAWTAMGGSTLYIETTKVEEREGKGDLVLTGQLGDVMKESAQIAHTVGRTVLLEKEPDNHFFANSKVHLHVPAGSTPKDGPSAGCTMITSMLSLAMGKPVKKDLAMTGEVTLTGRILPIGGVKEKTIAARRSAIKTLIFPAANKRDFDELASNVKEGLEVHFVDTYSEIYDLAFQSDAGTEMI

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1D6F4S1A0A1D6F4S1_MAIZE103647953984
A0A804MU88A0A804MU88_MAIZE103647953772
A0A804MU89A0A804MU89_MAIZE103647953982
A0A804MU91A0A804MU91_MAIZE103647953774

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias512-532Polar residues
Compositional bias533-547Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

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