A0A804HL01 · A0A804HL01_HUMAN

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentadherens junction
Cellular Componentcytoskeleton
Cellular Componentnuclear body
Cellular Componentnucleoplasm
Cellular Componentplasma membrane
Molecular Functionstructural constituent of cytoskeleton
Biological Processcell morphogenesis
Biological Processcell volume homeostasis
Biological Processcellular response to calcium ion
Biological Processerythrocyte differentiation
Biological Processhemoglobin metabolic process
Biological Processhomeostasis of number of cells within a tissue
Biological Processin utero embryonic development
Biological Processmulticellular organism growth
Biological Processpositive regulation of adherens junction organization
Biological Processpositive regulation of establishment of endothelial barrier

Names & Taxonomy

Subcellular Location

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 767 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Organism-specific databases

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)11PRIDEPhosphothreonine
Modified residue (large scale data)12PRIDEPhosphoserine
Modified residue (large scale data)24PRIDEPhosphotyrosine
Modified residue (large scale data)35PRIDEPhosphotyrosine
Modified residue (large scale data)59PRIDEPhosphoserine
Modified residue (large scale data)64PRIDEPhosphoserine
Modified residue (large scale data)353PRIDEPhosphoserine
Modified residue (large scale data)355PRIDEPhosphoserine
Modified residue (large scale data)358PRIDEPhosphoserine
Modified residue (large scale data)364PRIDEPhosphothreonine
Modified residue (large scale data)366PRIDEPhosphoserine
Modified residue (large scale data)408PRIDEPhosphoserine
Modified residue (large scale data)423PRIDEPhosphoserine
Modified residue (large scale data)427PRIDEPhosphoserine
Modified residue (large scale data)429PRIDEPhosphothreonine
Modified residue (large scale data)431PRIDEPhosphoserine
Modified residue (large scale data)436PRIDEPhosphoserine
Modified residue (large scale data)464PRIDEPhosphoserine
Modified residue (large scale data)465PRIDEPhosphoserine
Modified residue (large scale data)511PRIDEPhosphothreonine
Modified residue (large scale data)512PRIDEPhosphoserine
Modified residue (large scale data)514PRIDEPhosphoserine
Modified residue (large scale data)594PRIDEPhosphoserine
Modified residue (large scale data)612PRIDEPhosphotyrosine
Modified residue (large scale data)648PRIDEPhosphoserine
Modified residue (large scale data)662PRIDEPhosphoserine
Modified residue (large scale data)675PRIDEPhosphoserine
Modified residue (large scale data)676PRIDEPhosphothreonine
Modified residue (large scale data)707PRIDEPhosphoserine
Modified residue (large scale data)788PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

    • ENSG00000087274Expressed in right hemisphere of cerebellum and 208 other cell types or tissues

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-21Disordered
Domain147-329Class II aldolase/adducin N-terminal
Region423-470Disordered
Compositional bias437-453Basic and acidic residues
Compositional bias455-470Polar residues
Compositional bias638-664Basic and acidic residues
Region638-799Disordered
Compositional bias665-679Pro residues
Compositional bias716-731Basic and acidic residues
Compositional bias734-750Pro residues

Sequence similarities

Belongs to the aldolase class II family. Adducin subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    799
  • Mass (Da)
    87,700
  • Last updated
    2021-09-29 v1
  • Checksum
    30E40C295B5F2E83
MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQDAPLSDCTETIEGLELTEQTFSPAKSLSFRKGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKKSDS

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P35611ADDA_HUMANADD1737
E7EV99E7EV99_HUMANADD1632
D6RJE2D6RJE2_HUMANADD169
H0YFD8H0YFD8_HUMANADD1105
D6RF25D6RF25_HUMANADD1142
H0YG19H0YG19_HUMANADD1114
D6RAH3D6RAH3_HUMANADD1137
H0Y9H2H0Y9H2_HUMANADD1444
E7ENY0E7ENY0_HUMANADD1663

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias437-453Basic and acidic residues
Compositional bias455-470Polar residues
Compositional bias638-664Basic and acidic residues
Compositional bias665-679Pro residues
Compositional bias716-731Basic and acidic residues
Compositional bias734-750Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL121750
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL390065
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BX465861
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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