A0A803L7E5 · A0A803L7E5_CHEQI

Function

Catalytic activity

Cofactor

pyruvate (UniProtKB | Rhea| CHEBI:15361 )

Note: Binds 1 pyruvoyl group covalently per subunit.

Pathway

Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.

Features

Showing features for binding site, site, active site.

137650100150200250300350
Type
IDPosition(s)Description
Binding site24substrate
Binding site84substrate
Site84-85Cleavage (non-hydrolytic); by autolysis
Active site85Schiff-base intermediate with substrate; via pyruvic acid
Active site99Proton donor; for catalytic activity
Binding site242substrate
Active site248Proton acceptor; for processing activity
Active site261Proton acceptor; for processing activity
Binding site265substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylmethionine decarboxylase activity
Biological Processspermidine biosynthetic process
Biological Processspermine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    S-adenosylmethionine decarboxylase proenzyme
  • EC number

Organism names

  • Taxonomic identifier
  • Strain
    • cv. PI 614886
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > Caryophyllales > Chenopodiaceae > Chenopodioideae > Atripliceae > Chenopodium

Accessions

  • Primary accession
    A0A803L7E5

Proteomes

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_50423241581-84S-adenosylmethionine decarboxylase beta chain
Modified residue85Pyruvic acid (Ser); by autocatalysis
ChainPRO_504232415785-376S-adenosylmethionine decarboxylase alpha chain

Keywords

Family & Domains

Sequence similarities

Belongs to the eukaryotic AdoMetDC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    376
  • Mass (Da)
    41,429
  • Last updated
    2021-06-02 v1
  • Checksum
    B8C8B38F78946508
MTVPMAGDNNTTNNNEMAISAIGFEGFEKRLEISFFEPSIFVDPEGRGLRALTKAQLDEILGPAECTIVDSLANDDVDSYVLSESSLFVYAYKIIIKTCGTTKLLRAIPPILKLAESLSLDVKSVRYTRGSFIFPGAQSYPHRSFSEEVAVLDGYFGKLAAGSKAFVMGDSAKPQKWHVYCASAETISFDAPVYTLEMCMTGLNKERASVFFKSQSPNAAVMTESSGIRKILPDSKICDFDFEPCGYSMNAIEGSAISTIHITPEDGFSYASFEAVGYDLKKIDLNQLVERVLACFEPSEFSIAIHAEIAANSMEHNCFVNVNGYSREEGGIEELGFGDSSVFYQKFCKATRFAPKPKPALKCCWKEEIIEEGKDY

Keywords

Genome annotation databases

Similar Proteins

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