A0A7Z3HV31 · A0A7Z3HV31_9RICK

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site19-22ATP (UniProtKB | ChEBI)
Binding site61UMP (UniProtKB | ChEBI)
Binding site62ATP (UniProtKB | ChEBI)
Binding site66ATP (UniProtKB | ChEBI)
Binding site81UMP (UniProtKB | ChEBI)
Binding site142-149UMP (UniProtKB | ChEBI)
Binding site169ATP (UniProtKB | ChEBI)
Binding site170ATP (UniProtKB | ChEBI)
Binding site175ATP (UniProtKB | ChEBI)
Binding site178ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      GOY14_02150

Organism names

Accessions

  • Primary accession
    A0A7Z3HV31

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-223Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    247
  • Mass (Da)
    26,892
  • Last updated
    2021-06-02 v1
  • Checksum
    1B6354BB26EC1FAC
MAAATNRKSKVKYSRVLFKISGEALMGSRSFGHDMEVIDRLCKGVVDVYELGVQVCIVVGGGNIFRGVSASLSSCERAKSDHIGMLATVINALILRNFLEKKSVDSRVLSAIPMATICEPYIREKAINHLEKGRVVIFAAGIGNPFFTTDTAAALRAIETNCEVILKGTQVNGVYSSDPGENKDAIMYDKLSYTDLLTRDLKVMDASAVSLARDNSIPIIVFSLKREKIANVIKGFGTYTIVSDCQR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP046580
EMBL· GenBank· DDBJ
QKX01130.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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