A0A7Z3HV31 · A0A7Z3HV31_9RICK
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids247 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- ATP + UMP = ADP + UDP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 19-22 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KISG | ||||||
Binding site | 61 | UMP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 62 | ATP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 66 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 81 | UMP (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 142-149 | UMP (UniProtKB | ChEBI) | ||||
Sequence: IGNPFFTT | ||||||
Binding site | 169 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 170 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Binding site | 175 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 178 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rickettsiales > Anaplasmataceae > Wolbachieae > Wolbachia
Accessions
- Primary accessionA0A7Z3HV31
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 15-223 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: RVLFKISGEALMGSRSFGHDMEVIDRLCKGVVDVYELGVQVCIVVGGGNIFRGVSASLSSCERAKSDHIGMLATVINALILRNFLEKKSVDSRVLSAIPMATICEPYIREKAINHLEKGRVVIFAAGIGNPFFTTDTAAALRAIETNCEVILKGTQVNGVYSSDPGENKDAIMYDKLSYTDLLTRDLKVMDASAVSLARDNSIPIIVFS |
Sequence similarities
Belongs to the UMP kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length247
- Mass (Da)26,892
- Last updated2021-06-02 v1
- Checksum1B6354BB26EC1FAC
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP046580 EMBL· GenBank· DDBJ | QKX01130.1 EMBL· GenBank· DDBJ | Genomic DNA |