A0A7Z2QE25 · A0A7Z2QE25_9BACI

  • Protein
    Cytochrome c oxidase subunit 2
  • Gene
    coxB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

Catalytic activity

Cofactor

Cu cation (UniProtKB | Rhea| CHEBI:23378 )

Note: Binds a copper A center.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentrespirasome
Molecular Functioncopper ion binding
Molecular Functioncytochrome-c oxidase activity
Molecular Functionheme binding
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome c oxidase subunit 2
  • EC number

Gene names

    • Name
      coxB
    • ORF names
      GNK04_09640

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • N1-1
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus

Accessions

  • Primary accession
    A0A7Z2QE25

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane50-69Helical
Transmembrane89-108Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-121Cytochrome oxidase subunit II transmembrane region profile
Domain126-238Cytochrome oxidase subunit II copper A binding
Domain249-338Cytochrome c

Sequence similarities

Belongs to the cytochrome c oxidase subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    341
  • Mass (Da)
    37,999
  • Last updated
    2021-06-02 v1
  • Checksum
    BE4C754EABF4A9AA
MKRWRNVWRFLPLLSVIALALTGCGNEQLTAMLPKGEGAEMQFNLMMLSLYIMIGVFVVVALIYTVVLVRFRRRGESDNEIPEQTEGNVVLEILWTVVPIILLLILAVPTVMTTFALDEGTEKVPEGATVIKVTAHQYWWEFEYPDLEVKTSQDLHIPTGERVYFELVSKDVIHSFWVPTLGGKMDTNTATTNKMWLNAQEPGTYYGKCAELCGPSHALMDFKVIAQEKEDFEAWAEKMKEAGSQAASDQAAQGEEIFANSCIGCHAVGSEGGNTGPNLTNFGDREKVAGILDHTDKNIKDWISNPSEYKPGNNMPAFGDQLNDEELDALVVYLQGLKVEE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP046564
EMBL· GenBank· DDBJ
QHA94213.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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