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A0A7Y6TQ56 · A0A7Y6TQ56_9RICK

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 1 [2Fe-2S] cluster per subunit.
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionquinone binding
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase
  • EC number

Gene names

    • ORF names
      GO684_04770

Organism names

Accessions

  • Primary accession
    A0A7Y6TQ56

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-792Fe-2S ferredoxin-type
Domain79-1184Fe-4S His(Cys)3-ligated-type
Domain216-2724Fe-4S Mo/W bis-MGD-type

Sequence similarities

Belongs to the complex I 75 kDa subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    682
  • Mass (Da)
    75,764
  • Last updated
    2021-06-02 v1
  • MD5 Checksum
    0B4BF466471E03E3747B1581503F6F10
MIKVIINSQEYEVEPGLTIIQACETVGVEIPRFCYHERLAIAGNCRMCLVEVESGPLKPVASCAMPVTEGMVVHTDTPRVKKAREGVLEFLLINHPLDCPICDQGGECDLQDIAMVYGRGISRLDEHKRAIPKKHFGPLIETAMNRCIHCTRCVRFLSEVAGTNELGGIGRGENMEISTYVKKHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSSIRVDYRGPEIMRVLPRINEEVNEEWISDKTRFAYDGLKVQRLDQPYIKKDGRLVPADWNEALTVAAKKLRSTRPNEMAAIAGDLADCESMLLLKEIMQKLGSANIDCRQDGAKLIQNNRGSYVFNTTIEGIEDADLCLLINTNPKVEAPIINARIRKRYLQGNFPIASIGPDVKYLYHVEKLGNNPIILNEIAKGNHKFCKLLSAAQNPMLIIGQDALTRDDSESILALAGAIAEKFNMVRNDWNGFNMLHKAAARVGGLDIGFVPKKDGKNINQILEQAESGEIEVVYLLGADEINTLKLENTFVIYQGHHGDRGAHIADVILPGAAYTEKYATYVNTEGRVQKAKLAVSPPGEAKEDWSIIKNLSQYLGLSLPYDSLFDVRKKLSTIGPQFKNADQVVKNKWVSITCDEMKLSNTPFFLKECGFYMTDPISRASKIMADCTKAFYEHAN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WQMO01000032
EMBL· GenBank· DDBJ
NUY39907.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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