A0A7Y6AV94 · A0A7Y6AV94_9PSED

  • Protein
    Orotidine 5'-phosphate decarboxylase
  • Gene
    pyrF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site13substrate
Binding site35substrate
Active site62For OMPdecase activity
Binding site62-71substrate
Active site64For OMPdecase activity
Active site64Proton donor
Active site67For OMPdecase activity
Binding site122substrate
Binding site182substrate
Binding site191substrate
Binding site211substrate
Binding site212substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Orotidine 5'-phosphate decarboxylase
  • EC number
  • Alternative names
    • OMP decarboxylase
      (OMPDCase
      ; OMPdecase
      )

Gene names

    • Name
      pyrF
    • ORF names
      HNQ83_14885

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C2B4
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A7Y6AV94

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-227Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    232
  • Mass (Da)
    24,669
  • Last updated
    2021-06-02 v1
  • Checksum
    FB33D432D29A52FA
MSACQTPIIVALDFPTRDAALKLADQLDPKLCRVKVGKELFTSCASEIVGTLRDKGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLDKRSGPQPLLIGVTVLTSMEREDLAGIGLDIEPQEQVLRLAALAEKAGMDGLVCSALEAQALKSAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALEAGSDYLVIGRPISQAADPAKALADVVAELA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABFMU010000020
EMBL· GenBank· DDBJ
NUU36335.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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