A0A7Y6AUM8 · A0A7Y6AUM8_9PSED

  • Protein
    Thiol:disulfide interchange protein DsbD
  • Gene
    dsbD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionelectron transfer activity
Molecular Functionprotein-disulfide reductase (NAD(P)H) activity
Biological Processcytochrome complex assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Thiol:disulfide interchange protein DsbD
  • EC number
  • Alternative names
    • Protein-disulfide reductase
      (Disulfide reductase
      )

Gene names

    • Name
      dsbD
    • ORF names
      HNQ83_14615

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C2B4
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A7Y6AUM8

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane159-192Helical
Transmembrane204-226Helical
Transmembrane238-260Helical
Transmembrane281-311Helical
Transmembrane317-339Helical
Transmembrane351-373Helical
Transmembrane379-397Helical
Transmembrane409-430Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_503163388119-578Thiol:disulfide interchange protein DsbD
Disulfide bond118↔124Redox-active
Disulfide bond491↔494Redox-active

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain438-576Thioredoxin

Sequence similarities

Belongs to the thioredoxin family. DsbD subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    578
  • Mass (Da)
    61,811
  • Last updated
    2021-06-02 v1
  • Checksum
    B964F55BB7FE99E8
MRHLFLLFVLLISGVAQAGTNPFETKPEFLPVEKAFVFTSERLESGETQLYWQITDGYYLYQKRLKFDGLPAEHQPVLPPGESHSDEFFGEQQVYRQGLELKIPAGASGKIKVSFQGCADAGLCYPPQTKVVDLVGNGAVSSTNEAPDQALASNLQQRALGWSLLVFFGLGLLLAFTPCSLPMLPILAGLIVGSGASPKRGFALAGSYVVSMALVYAAMGVLAALLGANLQALLQNPWLLGSFAAIFVLLALPMFGYFELQLPVAVRDRLENVSRNQRGGSLLGAGVLGALSGLLVGPCMTAPLAGALLYIAQSGNALHGGLILFALGIGIGVPLLLLVTIGNRFLPKPGAWMNLVKGIFGFLFLATALLLLRPVLDESLWVGLCGALLLIAAYSAWKQSDGFGRIAHLFGASALLLGLWGSLLVIGAAGGSDDLFKPLQVFRASNSAVAAVPTGHDAFTTLKDPAALQRELDAAQAQGQWVLLDYYADWCVSCKVMEKQVFGKTKVLEALGDVRLLRLDVTADNAASRELLGRYKVPGPPSLLWIGADGVERRSQRITGEVDAETFLQRWTITRDAR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABFMU010000019
EMBL· GenBank· DDBJ
NUU36281.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp