A0A7Y5Z1T3 · A0A7Y5Z1T3_9PSED

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site18-21ATP (UniProtKB | ChEBI)
Binding site60UMP (UniProtKB | ChEBI)
Binding site61ATP (UniProtKB | ChEBI)
Binding site65ATP (UniProtKB | ChEBI)
Binding site80UMP (UniProtKB | ChEBI)
Binding site141-148UMP (UniProtKB | ChEBI)
Binding site168ATP (UniProtKB | ChEBI)
Binding site174ATP (UniProtKB | ChEBI)
Binding site177ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      HNO91_02985

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C7D2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A7Y5Z1T3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain13-222Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    247
  • Mass (Da)
    26,649
  • Last updated
    2021-06-02 v1
  • Checksum
    EF4D6CE271CEFD07
MAQQGSGYQARYKRILLKLSGEALMGSEEFGIDPKVLDRMALEVGQLVGIGVQVGLVIGGGNLFRGAALSAAGMDRVTGDHMGMLATVMNALAMRDALERANISAIVMSAISMVGVTDHYDRRKAMRHLNSKEVVIFAAGTGNPFFTTDSAACLRAIEIDADVVLKATKVDGVYTADPFKDPHAEKFDHLTYDEVLDRKLGVMDLTAICLCRDHKMPLRVFNMNKPGALLNIVHGGAEGTLIEEVQQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABFMR010000002
EMBL· GenBank· DDBJ
NUT85367.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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