A0A7Y5AS76 · A0A7Y5AS76_9GAMM

  • Protein
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • Gene
    fabA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-2-decenoyl-ACP and then its isomerization to Z-3-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site69

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function(3R)-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
Molecular Functiontrans-2-decenoyl-acyl-carrier-protein isomerase activity
Biological Processunsaturated fatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • EC number
  • Alternative names
    • 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA
    • Beta-hydroxydecanoyl thioester dehydrase
    • Trans-2-decenoyl-[acyl-carrier-protein] isomerase
      (EC:5.3.3.14
      ) . EC:5.3.3.14 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      fabA
    • ORF names
      HRH59_11180

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • YQF-2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Chromatiales > Chromatiaceae > Rheinheimera

Accessions

  • Primary accession
    A0A7Y5AS76

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the thioester dehydratase family. FabA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    170
  • Mass (Da)
    18,622
  • Last updated
    2021-06-02 v1
  • Checksum
    42FFE5087D4152E2
MTKNSFTKEDLIACANGELFGEGNSQLPSDNMLMMDRIIHISEEGGLYGKGQIIAELDITPDLWFFACHFKGDPVMPGCLGLDAMWQLVGFFLGWCEGPGKGRALGVGEVKFTGQILPTAKKVTYTINMKRVIKRKLFMGIADGVVSVDGRDIYAAEDLKVGLFQDTSSF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABSOD010000009
EMBL· GenBank· DDBJ
NRQ43104.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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