A0A7X6I123 · A0A7X6I123_9ACTN
- ProteinMycothiol acetyltransferase
- GenemshD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids308 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
Catalytic activity
- 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + CoA + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 36 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 80-82 | acetyl-CoA 1 (UniProtKB | ChEBI) | |||
Binding site | 181 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 230 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 239 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 243-245 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
Binding site | 250-256 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
Binding site | 278 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 283-288 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | mycothiol synthase activity | |
Molecular Function | peptide-alanine-alpha-N-acetyltransferase activity | |
Biological Process | mycothiol biosynthetic process | |
Biological Process | N-terminal peptidyl-alanine acetylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMycothiol acetyltransferase
- EC number
- Short namesMSH acetyltransferase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces
Accessions
- Primary accessionA0A7X6I123
Proteomes
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 8-141 | N-acetyltransferase | |||
Domain | 154-308 | N-acetyltransferase | |||
Sequence similarities
Belongs to the acetyltransferase family. MshD subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length308
- Mass (Da)33,654
- Last updated2021-06-02 v1
- ChecksumE33FEBD29967789B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAAVJD010000246 EMBL· GenBank· DDBJ | NJQ08115.1 EMBL· GenBank· DDBJ | Genomic DNA |