A0A7X6I123 · A0A7X6I123_9ACTN

  • Protein
    Mycothiol acetyltransferase
  • Gene
    mshD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

130820406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site361D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site80-82acetyl-CoA 1 (UniProtKB | ChEBI)
Binding site1811D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site2301D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site2391D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site243-245acetyl-CoA 2 (UniProtKB | ChEBI)
Binding site250-256acetyl-CoA 2 (UniProtKB | ChEBI)
Binding site2781D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site283-288acetyl-CoA 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmycothiol synthase activity
Molecular Functionpeptide-alanine-alpha-N-acetyltransferase activity
Biological Processmycothiol biosynthetic process
Biological ProcessN-terminal peptidyl-alanine acetylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mycothiol acetyltransferase
  • EC number
  • Short names
    MSH acetyltransferase
  • Alternative names
    • Mycothiol synthase

Gene names

    • Name
      mshD
    • ORF names
      HCN56_21655

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCL716
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A7X6I123

Proteomes

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-141N-acetyltransferase
Domain154-308N-acetyltransferase

Sequence similarities

Belongs to the acetyltransferase family. MshD subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    308
  • Mass (Da)
    33,654
  • Last updated
    2021-06-02 v1
  • Checksum
    E33FEBD29967789B
MSDVTVVDEVSAADQRDAGELIDAGARLDGQSAVSEQGRLLLRGGPREGVRHVMLRQKGELVAYGQLDGTDRVEAPAAELVVHPDHRGRGHGRAVGEALLAESGRRVRIWAHGGHPAARHLAQSLGLHLFRELWQLRRPLEGMPLPEPVLPDGIRVRPFVSGRDEEAWLELNAAAFAHHPEQGSLTRRDLDARMGEAWFDPAGFFLAVREKRTADGEPASEELLGFHWTKVHTAEGVGEIYVLGVGPGNQGLGLGKALTLVGLRYLAHDRGLPEAMLYVDADNTAAVRLYQSQGFATRETDLMYRTES

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAVJD010000246
EMBL· GenBank· DDBJ
NJQ08115.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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