A0A7X6CZT6 · A0A7X6CZT6_9ACTN

  • Protein
    Bifunctional (P)ppGpp synthetase/guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; ppGpp biosynthesis; ppGpp from GTP: step 1/2.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionhydrolase activity
Molecular Functionkinase activity
Biological Processguanosine tetraphosphate biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Bifunctional (P)ppGpp synthetase/guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase

Gene names

    • ORF names
      HCN56_07815

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCL716
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A7X6CZT6

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-19Pro residues
Region1-33Disordered
Domain98-195HD
Domain452-513TGS
Region622-645Disordered
Domain717-791ACT

Sequence similarities

Belongs to the relA/spoT family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    796
  • Mass (Da)
    88,173
  • Last updated
    2021-06-02 v1
  • Checksum
    687AC5C0338B61C0
RPAAPTPPPAPPAAAPAPQPPVSGISGRSGSSNRVRARLARLGVQRSTPYNPVLEPLLRVVRANDPKADTAVLRQLERAYQVAERWHRGQKRKSGDPYITHPLAVTTILAELGMDPATLMAGLLHDTVEDTEYGLDTLRRDFGDQVALLVDGVTKLDKVKFGEAAQAETVRKMVVAMAKDPRVLVIKLADRLHNMRTMRFLKREKQEQKARETLEIYAPLAHRLGMNTIKWELEDLAFAILYPKMYDEIVRLVAERAPKRDEYLATVIDEVLGDLRGARIKATVTGRPKHYYSVYQKMIVRGRDFAEIYDLVGIRVLVDSVRDCYGALGTVHARWNPVPGRFKDYIAMPKFNMYQSLHTTVIGPGGKPVELQIRTFDMHRRAEYGIAAHWKYKQQAVAGASKVRSDAPARKGEKAGEAVNDMAWLRQLLDWQKETEDPGEFLESLRFDLSRNEVFVFTPKGDVIALPAGATPVDFAYAVHTEVGHRTIGAKVNGRLVPLESTLDNGDTVEVFTSKASGAGPSRDWLGFVKSPRARNKIRGWFSRERRDEAIEQGKDAIVRAMRKQNLPIQHILTGDSLVTLAHEMRYPDISSLYAAIGENHVSAQSVVQKLVQAVGGEEAANEDVAETAPPVPASLGRRRSSGDPGVVVKGTDDVWVKLARCCTPVPGDPIIGFVTRGSGVSVHRADCVNVDALSREPERMLEVEWAPTQSSVFLVAIQVEALDRSRLLSDVTRILSDQHVNILSAAVQTSRDRVAISRFTFEMGDPKHLGHVLRAVRGVEGVYDVYRVTSARRGG

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias1-19Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAVJD010000038
EMBL· GenBank· DDBJ
NJQ05485.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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