A0A7X2NZC4 · A0A7X2NZC4_9RHOB

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Allosterically activated by GTP. Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site18-21ATP (UniProtKB | ChEBI)
Binding site60UMP (UniProtKB | ChEBI)
Binding site61ATP (UniProtKB | ChEBI)
Binding site65ATP (UniProtKB | ChEBI)
Binding site80UMP (UniProtKB | ChEBI)
Binding site141-148UMP (UniProtKB | ChEBI)
Binding site168ATP (UniProtKB | ChEBI)
Binding site174ATP (UniProtKB | ChEBI)
Binding site177ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      GB880_012205

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SMMA_5_TC
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Paracoccus

Accessions

  • Primary accession
    A0A7X2NZC4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region26-31Involved in allosteric activation by GTP

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    244
  • Mass (Da)
    26,461
  • Last updated
    2021-06-02 v1
  • MD5 Checksum
    25061B00876305ADF811363D4C95C6E7
MSDLAQKPAASYSRVMLKISGEALMGDQGYGLHPPTVARIAREVKSVHDLGVEICMVIGGGNIFRGLQGSAQGMERATADYMGMLATVMNALAMQAALEALNIHTRVISAIRMDEVCEPYIRRRAVRHLEKKRVCIFAAGTGNPYFTTDTAATLRANEMNCEAIFKGTKVDGVYDKDPAKFADAKRYDDVTYDEVLQQHLGVMDASAIALARDNDLPIIVFSLDEPGGFRGILAGSGTYTRVHG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP102355
EMBL· GenBank· DDBJ
UXU80537.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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