A0A7X2NZC4 · A0A7X2NZC4_9RHOB
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids244 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- UMP + ATP = UDP + ADP
Activity regulation
Allosterically activated by GTP. Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 18-21 | ATP (UniProtKB | ChEBI) | |||
Binding site | 60 | UMP (UniProtKB | ChEBI) | |||
Binding site | 61 | ATP (UniProtKB | ChEBI) | |||
Binding site | 65 | ATP (UniProtKB | ChEBI) | |||
Binding site | 80 | UMP (UniProtKB | ChEBI) | |||
Binding site | 141-148 | UMP (UniProtKB | ChEBI) | |||
Binding site | 168 | ATP (UniProtKB | ChEBI) | |||
Binding site | 174 | ATP (UniProtKB | ChEBI) | |||
Binding site | 177 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Paracoccus
Accessions
- Primary accessionA0A7X2NZC4
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Structure
Sequence
- Sequence statusComplete
- Length244
- Mass (Da)26,461
- Last updated2021-06-02 v1
- MD5 Checksum25061B00876305ADF811363D4C95C6E7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP102355 EMBL· GenBank· DDBJ | UXU80537.1 EMBL· GenBank· DDBJ | Genomic DNA |