A0A7X2JDV8 · A0A7X2JDV8_9FIRM

  • Protein
    Polyamine aminopropyltransferase
  • Gene
    speE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site31S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site86spermidine (UniProtKB | ChEBI)
Binding site106S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site137-138S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Active site155Proton acceptor
Binding site155-158spermidine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionspermidine synthase activity
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyamine aminopropyltransferase
  • Alternative names
    • Putrescine aminopropyltransferase
      (PAPT
      )
    • Spermidine synthase
      (SPDS
      ; SPDSY
      ) (EC:2.5.1.16
      ) . EC:2.5.1.16 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      speE
    • ORF names
      GKG43_12160

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BIOML-A2
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Eubacteriaceae > Eubacterium

Accessions

  • Primary accession
    A0A7X2JDV8

Proteomes

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-237PABS

Sequence similarities

Belongs to the spermidine/spermine synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    284
  • Mass (Da)
    33,157
  • Last updated
    2021-06-02 v1
  • Checksum
    DD729915AF0A5BFE
MDFWVSEMHTNNVKISIRAERQLFSAQSEFQRLDIFETPEFGKVLTSNGNVIFTEKDEFIYDEMIVHVPMAVHPHVKNVLVLGGGDGGVARELSYYEEIEHIDVVEADQLFVYACREHFPEDANGLDDDRVSMYYEDGLKFLRSRQDAYDLIINDCTDPLGHAAGLFTKEFYGSCFQALHEDGIMVYQHGSPFYAEDEESCRIMHRKAYRSFPVNRVYQAHIPTCPAGYWLFGFASKKYHPLRNLDAKRWREREIQTRYYTTNLHTGAFMLPRYVEDLLEEEEV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WKZK01000030
EMBL· GenBank· DDBJ
MSD06884.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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