A0A7X1J745 · A0A7X1J745_9ACTN

  • Protein
    Multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; succinyl-CoA from 2-oxoglutarate (dehydrogenase route): step 1/1.

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentoxoglutarate dehydrogenase complex
Molecular Function2-oxoglutarate decarboxylase activity
Molecular Functionacyltransferase activity
Molecular Functionmagnesium ion binding
Molecular Functionoxoglutarate dehydrogenase (succinyl-transferring) activity
Molecular Functionthiamine pyrophosphate binding
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
      (EC:4.1.1.71
      )

Gene names

    • ORF names
      H4N64_28485

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • PSKA01
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A7X1J745

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for compositional bias, region, coiled coil, domain.

Type
IDPosition(s)Description
Compositional bias1-19Polar residues
Region1-25Disordered
Region67-134Disordered
Compositional bias70-121Pro residues
Coiled coil817-844
Domain906-1099Transketolase-like pyrimidine-binding

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,254
  • Mass (Da)
    137,087
  • Last updated
    2021-06-02 v1
  • Checksum
    89C2A7149E21514F
MSPQSPSNSSISTTDQAGKSPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPGAAAASAPAAPAAPAPAPAAPAPAAVPAPAPAAPKPAAAAPAAPAPAAAAPAPAPAKPAAKPAPKAAPATAAPEGPELVTLRGPAAAVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPAMNYAFGEKDGKPTLIKPAHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDDVFESLRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSLMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGHTKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVSRAKQDVINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQGQLEKVFTEVREATAQPATAEPSEPQAEFPVAVNTAVTAEVVKRIAESQVNIPDSITVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDRETGDEFTPLMYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDASVDPAAVRKVVFCAGKVYYDLEAERQKRGATDVAIIRIERLYPLPGAELQAEIAKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRRHGSSPAVGSAKRHQAEQEQLVREVFEA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-19Polar residues
Compositional bias70-121Pro residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACMSF010000036
EMBL· GenBank· DDBJ
MBC2905441.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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