A0A7W9WRV6 · A0A7W9WRV6_9BURK

Function

function

Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP-dependent cleavage of peptide bonds with broad specificity.
    EC:3.4.25.2 (UniProtKB | ENZYME | Rhea)

Activity regulation

Allosterically activated by HslU binding.

Features

Showing features for active site, binding site.

117820406080100120140160
TypeIDPosition(s)Description
Active site7
Binding site162Na+ (UniProtKB | ChEBI)
Binding site165Na+ (UniProtKB | ChEBI)
Binding site168Na+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentHslUV protease complex
Cellular Componentproteasome core complex
Molecular Functionmetal ion binding
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent protease subunit HslV
  • EC number

Gene names

    • Name
      hslV
    • ORF names
      F4827_000879

Organism names

  • Taxonomic identifier
  • Strain
    • WP4_2_2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia

Accessions

  • Primary accession
    A0A7W9WRV6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.

Family & Domains

Sequence similarities

Belongs to the peptidase T1B family. HslV subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    178
  • Mass (Da)
    18,993
  • Last updated
    2021-06-02 v1
  • Checksum
    16D31C995B14954F
MEQFHGTTIVSVRRGDKVALGGDGQVTLGNIVMKGGAKKVRRIYGGKVMVGFAGGTADAFSLLDRFEAKLEKHQGNLTRAAVELAKDWRTDRMLRRLEAMLIAADATTTLVITGNGDVLDPEGGICAIGSGGSYAQAAAKALVDNTDLSPREIVEKSLEIAGDMCIYTNHNRVIETIE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACHBW010000002
EMBL· GenBank· DDBJ
MBB6101053.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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