A0A7W9U2V2 · A0A7W9U2V2_9BURK

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site14ADP (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site14sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site16ATP (UniProtKB | ChEBI)
Binding site18ADP (UniProtKB | ChEBI)
Binding site84glycerol (UniProtKB | ChEBI)
Binding site84sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site85glycerol (UniProtKB | ChEBI)
Binding site85sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site136glycerol (UniProtKB | ChEBI)
Binding site136sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site245glycerol (UniProtKB | ChEBI)
Binding site245sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site246glycerol (UniProtKB | ChEBI)
Binding site267ADP (UniProtKB | ChEBI)
Binding site267ATP (UniProtKB | ChEBI)
Binding site310ADP (UniProtKB | ChEBI)
Binding site310ATP (UniProtKB | ChEBI)
Binding site314ATP (UniProtKB | ChEBI)
Binding site411ADP (UniProtKB | ChEBI)
Binding site411ATP (UniProtKB | ChEBI)
Binding site415ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      F4827_005764

Organism names

  • Taxonomic identifier
  • Strain
    • WP4_2_2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia

Accessions

  • Primary accession
    A0A7W9U2V2

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-252Carbohydrate kinase FGGY N-terminal
Domain262-450Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    501
  • Mass (Da)
    54,726
  • Last updated
    2021-06-02 v1
  • Checksum
    2869E826DA40760D
MQDQQYILALDQGTTSSRAMLFDRQGRIVSTAQKEFEQIYPRPGWVEHDPQEIWSTQAGVAAEAVTRAGMNGTNIAAIGITNQRETTIVWDRETGQPIYNAIVWQDRRTADFCDQLKAQGLEEKVRAKTGLPIDSYFSGTKIRWILDNVEGAREKARQGKLAFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTRQWDNELLEALDIPRNMLPEVRSSSEIYGPTKTTVFASKIPLAGIAGDQQAALFGQMCTHTGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDQVNYALEGSIFIAGAVVQWLRDGMGIIKSASEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSLFGVTRGTTSAHVARAALDSIAYQSLDVLAAMEADSGISVGELRVDGGASANNLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAVGYWKNVDELQGQWHVDKRFAPNMAASQVDACRAGWQRAVRAAKAWADDSQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACHBW010000020
EMBL· GenBank· DDBJ
MBB6105894.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp