A0A7W9HGB0 · A0A7W9HGB0_9PSEU

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site66substrate
Binding site150substrate
Binding site212substrate
Binding site242substrate
Binding site246substrate
Binding site247NAD+ (UniProtKB | ChEBI)
Binding site276-281NAD+ (UniProtKB | ChEBI)
Binding site278-283NAD+ (UniProtKB | ChEBI)
Binding site299NAD+ (UniProtKB | ChEBI)
Binding site334NAD+ (UniProtKB | ChEBI)
Binding site403NAD+ (UniProtKB | ChEBI)
Binding site410NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • ORF names
      F4560_001234

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 45486
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Saccharothrix

Accessions

  • Primary accession
    A0A7W9HGB0

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain247-409S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    489
  • Mass (Da)
    52,797
  • Last updated
    2021-06-02 v1
  • Checksum
    FD8235D3C28DAF86
MTIQLTADSGGSVADFKVADLSLAPFGRKEIQLAEQEMPGLMALRREYGPQQPLAGKKIAGSLHMTIQTAVLIETLAALGADVRWVSCNIFSTQDHAAAAVVVGPEGTVDNPKGSSVFAWKGETLEEYWWCTEQLLTWPDGSGPDSIVDDGGDATLLVHMGVEYEAAGAVPSSAEDDSDDHKLILESLRRSLASSPTRYTDMAKSIIGVTEETTNGVNRLYQLHKAGKLLFAGINVNDSVTKSKFDNKYGIRHSLIDGINRATDVMIAGKLAVVCGYGDVGKGAVESLRGQGARVVVTEIDPICALQAAMDGLNVVLLEDVIADGDIFITTTGNRDIIMAEDMAKMKHNAVVGNVGHFDNEIDMAGLAKVPGIERIEIKPQVHEWKFADGHSIIVLSEGRLLNLGNATGHPSFVMSSSFSNQTIAQIELYTKREEYGVGVYMLPKHLDEKVARMHLSAVGAKLTPLTKVQAEYLGVDENGPYKPDHYRY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACHMO010000001
EMBL· GenBank· DDBJ
MBB5801466.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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