A0A7W6S2I1 · A0A7W6S2I1_9PROT

  • Protein
    4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
  • Gene
    ispE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site29
Binding site116-126ATP (UniProtKB | ChEBI)
Active site158

GO annotations

AspectTerm
Molecular Function4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
Molecular FunctionATP binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processphosphorylation
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
  • EC number
  • Short names
    CMK
  • Alternative names
    • 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase

Gene names

    • Name
      ispE
    • ORF names
      GGD88_003281

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • JA135
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Rhodospirillaceae > Roseospira

Accessions

  • Primary accession
    A0A7W6S2I1

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain108-165GHMP kinase N-terminal
Domain225-293GHMP kinase C-terminal

Sequence similarities

Belongs to the GHMP kinase family. IspE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    318
  • Mass (Da)
    32,564
  • Last updated
    2021-06-02 v1
  • Checksum
    9A78A376B29C0434
MSTADEDTRATAETAADMATTLRAAAPAKVNLYLHVTGRRADGYHLLDSLMAFAAVHDVVTVAPADDLSLTVDGPNAAALADLDPSDNLILRAARALAETAGVAACARLTLTKHLPVAGGIGGGSADAAAALRGLYRLWDLTLDDATMLDLALGLGADVPVCLYGRAAHVSGIGEVLDPAPALPAAPLLLVNAGAPVSTPEVFGRRRGPFSRPAPLRDAPVNALALAQDLAGRGNDLEPPARTLCDAVGETLDLLTAQAGALLTRMSGSGGTCFALFASEAEAEAARRAIAEARPHWWVARTRLVDDARALAPDPPSA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACIGI010000040
EMBL· GenBank· DDBJ
MBB4287531.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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