A0A7W3NS47 · A0A7W3NS47_STRMR

  • Protein
    Alkyl hydroperoxide reductase AhpD
  • Gene
    ahpD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

117720406080100120140160
TypeIDPosition(s)Description
Active site131Proton donor
Active site134Cysteine sulfenic acid (-SOH) intermediate

GO annotations

AspectTerm
Molecular Functionalkyl hydroperoxide reductase activity
Molecular Functiondisulfide oxidoreductase activity
Molecular Functionhydroperoxide reductase activity
Molecular Functionperoxiredoxin activity
Biological Processcell redox homeostasis
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alkyl hydroperoxide reductase AhpD
  • EC number
  • Alternative names
    • Alkylhydroperoxidase AhpD

Gene names

    • Name
      ahpD
    • ORF names
      HDA42_004876

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 41827
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A7W3NS47

Proteomes

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond131↔134
Disulfide bond134Interchain (with AhpC); in linked form

Keywords

Interaction

Subunit

Homotrimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain96-177Carboxymuconolactone decarboxylase-like

Sequence similarities

Belongs to the AhpD family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    177
  • Mass (Da)
    19,075
  • Last updated
    2021-06-02 v1
  • Checksum
    975B16E7485ACC5D
MSLDSLKSRVPDYAKDLKLNLGSVIGNSDLPAQQLWGTVLATAIASRSPIVLRELEPEAKANLSPEAYTAAKSAAAIMAMNNVFYRTRHLLSDHEYGTLRAGLRMNVIGNPGVEKVDFELWSFAVSAINGCGMCLDSHEQVLRKAGMERDTIQEAFKIAAVVQAVGATLEAEAVLAE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACJIJ010000002
EMBL· GenBank· DDBJ
MBA9055698.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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