A0A7W2ILR6 · A0A7W2ILR6_9BURK

  • Protein
    Uridylate kinase
  • Gene
    pyrH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site12-15ATP (UniProtKB | ChEBI)
Binding site54UMP (UniProtKB | ChEBI)
Binding site55ATP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site74UMP (UniProtKB | ChEBI)
Binding site135-142UMP (UniProtKB | ChEBI)
Binding site162ATP (UniProtKB | ChEBI)
Binding site168ATP (UniProtKB | ChEBI)
Binding site171ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      H3H39_16985

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LX47W
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Oxalobacteraceae > Telluria group > Rugamonas

Accessions

  • Primary accession
    A0A7W2ILR6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-216Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    238
  • Mass (Da)
    25,389
  • Last updated
    2021-06-02 v1
  • Checksum
    357ACD663478DA70
MSKPAYKRVLLKLSGEALMGDDPYGINRGTIERMVADVAEVAKMGVELAIVIGGGNIFRGVAPGAQGMDRATADYMGMLATVMNALALADAMRHVGITARVMSAIGIEQVVEPYVRPKALQYLEEGKVVVFAAGTGNPFFTTDTAAALRGSEMSAEIVLKATKVDGVYTADPKKDPHATLFQTITFDEAIAKHLQVMDATAFALCRDQKLPIKVFSITKPGALMRVVMGEDEGTLVHV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACEZU010000008
EMBL· GenBank· DDBJ
MBA5688741.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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