A0A7W2HDW4 · A0A7W2HDW4_9ACTN
- ProteinDNA polymerase beta
- GenepolX
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids575 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+
- a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA = (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | exonuclease activity | |
Molecular Function | phosphoric ester hydrolase activity | |
Molecular Function | zinc ion binding | |
Biological Process | bacterial-type flagellum-dependent swarming motility | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase beta
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces > Streptomyces himalayensis
Accessions
- Primary accessionA0A7W2HDW4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-316 | DNA-directed DNA polymerase X | ||||
Sequence: RPNEEVEALLKEYADLIAITHGDAFKARVYEKAARAIGGHPRDVSQLDAAELRDIPGVGKSIAEKVVEYFRTGRITAVEETRAKIPAGLRELITIPTLGPKKAMTLYEDLHISSVSELADAIHAEKLRDLKGFGEKTEQNILHGIALLQQAGDRILLSMAMEQAEEVVAQLSGVTGCQSCTYAGSLRRMKETIGDIDILVAAGRSAPFMDALSELPATAEVIAHGEKKTSIRTTKGLQIDLRVLPPDSWGAGLQYFTGSKAHNIRTRTIAVRQGLKLSEYGLFETESGKSVASRSEEDVYARLGLPWIPPTLRE | ||||||
Domain | 52-71 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: AELRDIPGVGKSIAEKVVEY | ||||||
Domain | 92-111 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: RELITIPTLGPKKAMTLYED | ||||||
Domain | 127-146 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: EKLRDLKGFGEKTEQNILHG | ||||||
Domain | 340-418 | Polymerase/histidinol phosphatase N-terminal | ||||
Sequence: GDLHTHTDLTDGLAPLEEMVEAAAQRGYAYYAITDHAPNLYMQRMTDEKILAQREQVRELDGKYHRMRLLHGTELNIGP |
Family and domain databases
Sequence
- Sequence statusComplete
- Length575
- Mass (Da)63,519
- Last updated2021-06-02 v1
- Checksum845CB90C6A7E108B