A0A7W2D052 · A0A7W2D052_9ACTN
- ProteinThreonine--tRNA ligase
- GenethrS
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids658 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H+ + L-threonyl-tRNA(Thr)
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | threonine-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Biological Process | threonyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThreonine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces > Streptomyces himalayensis
Accessions
- Primary accessionA0A7W2D052
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-61 | TGS | ||||
Sequence: MSDVRVIIHRDSEREERVVTTGTTAADLFAGERTIVAARVDGQLKDLAYAIKDGEKVEPVE | ||||||
Domain | 250-554 | Aminoacyl-transfer RNA synthetases class-II family profile | ||||
Sequence: DFLAEAEKRDHRKLGSELDLFSIPDQIGSGLAVFHPKGGIIRRVMEDYSRRRHEEEGYEFVYTPHATKGKLFETSGHLDWYADGMYPPMQLDEGVDYYLKPMNCPMHNLIFDARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRARGFTQDDAHIYCTKEQMADELDSTLTFVLNLLRDYGLTDFYLELSTKDPEKFVGSDEVWEEATETLRKVAEKQGLPLVPDPGGAAFYGPKISVQAKDAIGRTWQMSTVQLDFNLPERFNLEYTGPDGSKQRPVMIHRALFGSIERFFAVLLEHYAGAFP |
Sequence similarities
Belongs to the class-II aminoacyl-tRNA synthetase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length658
- Mass (Da)74,470
- Last updated2021-06-02 v1
- Checksum98A7B3F66926875F