A0A7W1CG79 · A0A7W1CG79_UNCAI
- ProteinDNA 5'-3' helicase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids551 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
- Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction. This creates two antiparallel DNA single strands (ssDNA). The leading ssDNA polymer is the template for DNA polymerase III holoenzyme which synthesizes a continuous strand.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | DNA helicase activity | |
Molecular Function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | |
Molecular Function | nucleic acid binding | |
Biological Process | nucleobase-containing compound metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA 5'-3' helicase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Acidobacteriota
Accessions
- Primary accessionA0A7W1CG79
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 10-283 | Helicase ATP-binding | ||||
Sequence: LIAKYHKDYEYRFGQIKMAEAVLRAFEEKKHLIVEAGTGTGKTLAYLVPAIAAALGQKKRIIISTGTKNLQEQLMEKDIPFLQRIMPKKFTAAYMKGRSNYACLYRIGKAESQPILDGLDEMDYFDEIRHWARESPTGDRAELTTMPENLSFWGRINAKSETCLGQKCPDFEPCFITRMRGRADEADIVIVNHHLFFADLNLRGNEYGRVIPDYSAVIFDEAHLIEDIAADYFGFQVSTFQIDELVRDSENLPITDAIVTRDLTKLAARIIGLA |
Sequence similarities
Belongs to the helicase family. DinG subfamily.
Family and domain databases
Sequence
- Sequence statusFragment
- Length551
- Mass (Da)62,326
- Last updated2021-06-02 v1
- ChecksumC0CCF053DAB43879
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 551 | |||||
Sequence: S |