A0A7W0YAL3 · A0A7W0YAL3_UNCDE
- Protein3'-phosphate/5'-hydroxy nucleic acid ligase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids405 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 75 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 167-171 | GMP (UniProtKB | ChEBI) | |||
Binding site | 168 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 185 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 278 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 278-279 | GMP (UniProtKB | ChEBI) | |||
Binding site | 310-313 | GMP (UniProtKB | ChEBI) | |||
Binding site | 317 | GMP (UniProtKB | ChEBI) | |||
Active site | 334 | GMP-histidine intermediate | |||
Binding site | 334-337 | GMP (UniProtKB | ChEBI) | |||
Binding site | 404 | GMP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA ligase activity | |
Molecular Function | GTP binding | |
Molecular Function | manganese ion binding | |
Biological Process | DNA repair | |
Biological Process | RNA processing | |
Biological Process | RNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3'-phosphate/5'-hydroxy nucleic acid ligase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Myxococcota > Myxococcia
Accessions
- Primary accessionA0A7W0YAL3
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length405
- Mass (Da)43,622
- Last updated2021-06-02 v1
- ChecksumBB0C908754A80AEB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACCSS010001100 EMBL· GenBank· DDBJ | MBA3542333.1 EMBL· GenBank· DDBJ | Genomic DNA |