A0A7V8RMN9 · A0A7V8RMN9_9PSED
- ProteinBifunctional chorismate mutase/prephenate dehydratase
- GenepheA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids364 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
Catalytic activity
- H+ + prephenate = 3-phenylpyruvate + CO2 + H2O
Pathway
Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.
Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 264 | Essential for prephenate dehydratase activity | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | chorismate mutase activity | |
Molecular Function | prephenate dehydratase activity | |
Biological Process | chorismate metabolic process | |
Biological Process | L-phenylalanine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBifunctional chorismate mutase/prephenate dehydratase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A7V8RMN9
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-95 | Chorismate mutase | ||||
Sequence: MSEQELKALRLRIDALDEKVLELISERARCAQEVARVKMASLAEGEVPVFYRPEREAQVLKRVMERNKGPLGNEEMARLFREIMSSCLALEQPLK | ||||||
Domain | 95-271 | Prephenate dehydratase | ||||
Sequence: KVAYLGPEGTFTQAAAMKHFGHAVISKPMAAIDEVFREVAAGAVNFGVVPVENSTEGAVNHTLDSFLEHDMVICGEVELRIHHHLLVGENTKTDSISRIYSHAQSLAQCRKWLDAHYPNVERVAVSSNAEAAKRVKGEWNSAAIAGDMAAGLYGLTRLAEKIEDRPDNSTRFLMIGS | ||||||
Domain | 283-360 | ACT | ||||
Sequence: SIIVSMSNKPGALHELLVPFHDNGIDLTRIETRPSRSGKWTYVFFIDFVGHHRDPLVKGVLEKISQEAVALKVLGSYP |
Family and domain databases
Sequence
- Sequence statusComplete
- Length364
- Mass (Da)40,316
- Last updated2021-06-02 v1
- Checksum08AE76050D1D46B3
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VDLV01000026 EMBL· GenBank· DDBJ | MBA1379309.1 EMBL· GenBank· DDBJ | Genomic DNA |