A0A7U3W2V4 · A0A7U3W2V4_DIOJA
- ProteinATP-dependent Clp protease proteolytic subunit
- GeneclpP
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids203 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
Catalytic activity
- Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 100 | |||||
Sequence: S | ||||||
Active site | 100 | Nucleophile | ||||
Sequence: S | ||||||
Active site | 125 | |||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast stroma | |
Cellular Component | endopeptidase Clp complex | |
Molecular Function | ATP-dependent peptidase activity | |
Molecular Function | ATPase binding | |
Molecular Function | serine-type endopeptidase activity | |
Biological Process | protein quality control for misfolded or incompletely synthesized proteins |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent Clp protease proteolytic subunit
- EC number
- Alternative names
Gene names
Encoded on
- Chloroplast
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Dioscoreales > Dioscoreaceae > Dioscorea
Accessions
- Primary accessionA0A7U3W2V4
Subcellular Location
Interaction
Subunit
Component of the chloroplastic Clp protease core complex.
Structure
Sequence
- Sequence statusComplete
- Length203
- Mass (Da)22,724
- Last updated2021-06-02 v1
- ChecksumE96A286CFBC7F3FA