A0A7U3TX47 · A0A7U3TX47_9TRAC

  • Protein
    NADH-quinone oxidoreductase subunit N
  • Gene
    ndhB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentplastid
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit N
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit N
    • NDH-1 subunit N

Gene names

    • Name
      ndhB
    • Synonyms
      nuoN

Encoded on

  • Plastid

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 110-kb
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Lycopodiopsida > Selaginellales > Selaginellaceae > Selaginella

Accessions

  • Primary accession
    A0A7U3TX47

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-29Helical
Transmembrane41-61Helical
Transmembrane81-100Helical
Transmembrane107-125Helical
Transmembrane165-185Helical
Transmembrane205-226Helical
Transmembrane246-266Helical
Transmembrane278-297Helical
Transmembrane304-322Helical
Transmembrane328-352Helical
Transmembrane373-395Helical
Transmembrane407-428Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-97NAD(P)H-quinone oxidoreductase subunit 2 N-terminal
Domain128-423NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    496
  • Mass (Da)
    53,805
  • Last updated
    2021-06-02 v1
  • Checksum
    E8CCE8D534FB9E2D
MESGFGLRFLYGSTILPECILILSLIILLTIDLTSEGDTYWSYPISLTGSVTGITVLFSQWREEPIISLLCGPQTNTCDDIFQFLILLCLILCAPLFAEYFQCTEMAVTESLFFALAATLGGMFLCCASDLVTIFVALECSSLCFYLLSGCTSRDVRSGEATMKYLLLGGTSSSILVYGFSWLYGLSGGEVQLWGILNGLVESKMQNSAGTSIALVCIMVGIVFKLSLVPFHQWTPDVYEGSPTPVVAFLSVTSKVAALALATRIFNLFSPFSDEWHLLLEILAILSMILGNFIAIAQTSMKRMLAYSSISQIGYIMIGIIAGNPSGYASMLTYTLFYIFVNLGAFACIALFSLRTGTDSIRDCAGLYGQDPLLALCLTLCLLSLGGFPPLSGFFGKLYLFWCGWQAGLYLLVSTGLVASVISMYCYLKIIKLLMGGRGRKLATPRTGDNIIPSFSSLHTPESLIELSMMLCVIASTTLGLAMNPITTIARDNIPN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MK293726
EMBL· GenBank· DDBJ
QQP00258.1
EMBL· GenBank· DDBJ
Genomic DNA
MK293726
EMBL· GenBank· DDBJ
QQP00289.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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