A0A7T4QXU7 · A0A7T4QXU7_9GAMM
- ProteinLexA repressor
- GenelexA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids200 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Catalytic activity
Features
Showing features for dna binding, site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
DNA binding | 28-48 | H-T-H motif | |||
Site | 82-83 | Cleavage; by autolysis | |||
Active site | 117 | For autocatalytic cleavage activity | |||
Active site | 154 | For autocatalytic cleavage activity | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA binding | |
Molecular Function | serine-type endopeptidase activity | |
Biological Process | DNA repair | |
Biological Process | DNA replication | |
Biological Process | negative regulation of DNA-templated transcription | |
Biological Process | proteolysis | |
Biological Process | SOS response |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLexA repressor
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Cellvibrionales > Spongiibacteraceae > Spongiibacter
Accessions
- Primary accessionA0A7T4QXU7
Proteomes
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length200
- Mass (Da)22,189
- Last updated2021-09-29 v1
- ChecksumE1C3EB5EBC67BDBE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP066167 EMBL· GenBank· DDBJ | QQD16736.1 EMBL· GenBank· DDBJ | Genomic DNA |