A0A7T3F9C1 · A0A7T3F9C1_9MICC
- ProteinRiboflavin synthase
- GeneribB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids664 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
Catalytic activity
- GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H+
Cofactor
Pathway
Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.
Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 3,4-dihydroxy-2-butanone-4-phosphate synthase activity | |
Molecular Function | GTP binding | |
Molecular Function | GTP cyclohydrolase II activity | |
Molecular Function | metal ion binding | |
Molecular Function | riboflavin synthase activity | |
Biological Process | riboflavin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRiboflavin synthase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Micrococcaceae > Rothia
Accessions
- Primary accessionA0A7T3F9C1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for repeat, domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Repeat | 1-99 | Lumazine-binding | |||
Domain | 1-99 | Lumazine-binding | |||
Repeat | 100-201 | Lumazine-binding | |||
Domain | 100-201 | Lumazine-binding | |||
Region | 210-247 | Disordered | |||
Sequence similarities
In the N-terminal section; belongs to the DHBP synthase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length664
- Mass (Da)69,208
- Last updated2021-09-29 v1
- ChecksumABA3D0997A25CA3F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP065738 EMBL· GenBank· DDBJ | QPT53305.1 EMBL· GenBank· DDBJ | Genomic DNA |