A0A7T1S022 · A0A7T1S022_9EUKA

  • Protein
    NADH-ubiquinone oxidoreductase chain 5
  • Gene
    nad5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial respiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number

Gene names

    • Name
      nad5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Haptista > Haptophyta > Pavlovales > Pavlovaceae > Diacronema

Accessions

  • Primary accession
    A0A7T1S022

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-48Helical
Transmembrane55-77Helical
Transmembrane83-101Helical
Transmembrane113-130Helical
Transmembrane136-157Helical
Transmembrane169-189Helical
Transmembrane209-231Helical
Transmembrane252-273Helical
Transmembrane279-299Helical
Transmembrane311-337Helical
Transmembrane343-362Helical
Transmembrane374-395Helical
Transmembrane415-438Helical
Transmembrane459-480Helical
Transmembrane521-543Helical
Transmembrane625-643Helical
Transmembrane649-674Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain64-114NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Domain130-420NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain515-642NADH dehydrogenase subunit 5 C-terminal

Sequence similarities

Belongs to the complex I subunit 5 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    677
  • Mass (Da)
    75,445
  • Last updated
    2021-06-02 v1
  • Checksum
    A862ED478A0B9878
MYLVIIATPLLSFLVATTLGRFLGSRGVCLLSTFCTFFAFFLALSIFYEVGLCKAICSIKIFSWMVSDTFVVGWGFLFDNLSASMLIVVTSVSALVHLYAIGYMENDPHQTRFMSYLSLFTFFMLILVTADNYMQMFVGWEGVGLVSYLLISFWNTRIQANKSAIKAMLVNRVGDIGLCLGLCGIFILFHSLEYTTIFSLAASLNYASFNFFGFTFSFIDLLCFLIFWGAVGKSAQIGLHTWLPDAMEGPTPVSALIHAATMVTAGVFVIIRSAPLFELTPSVLCLVSVVGASTAFFAASSGLVQNDLKRVIAYSTCSQLGYMVFACGLSNYSVAFFHLANHAFFKALLFLGAGCIIHGICDEQDMRKMGLGKIFMFTYTFILIGSLALAGFPFLTGFYSKDAILELALANYTWVGAFTHTLGLLAAFCTSIYAFRLLHLSFLNTHNSYKLYVSSAHEAPFTMAFPLFVLSFGAIFVGYMTKDFMIGLGVDSWNGVLFVSHKNSALIEAEFLFAYQKHLPFFLGFAGAFFAYLLISSTLSLPWKRGIFSLLKRSSFYLNFYKFLSAKWHFDQVYNEYIAQSLMHVGYRKTFLLLDKGFVESLGPFGFSEYISTFSSKISHHLTGYLYHYALVFILIVAVFIISSDFLSLAASFGVLAPIYMSLLCSFFMIDLVFNQE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MW044629
EMBL· GenBank· DDBJ
QPO84604.1
EMBL· GenBank· DDBJ
Genomic DNA
MW044630
EMBL· GenBank· DDBJ
QPO84624.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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