A0A7S9WI21 · A0A7S9WI21_9RHOB

  • Protein
    Riboflavin biosynthesis protein RibD
  • Gene
    ribD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion.

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.
Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site44Zn2+ (UniProtKB | ChEBI); catalytic
Active site46Proton donor
Binding site69Zn2+ (UniProtKB | ChEBI); catalytic
Binding site78Zn2+ (UniProtKB | ChEBI); catalytic
Binding site148NADP+ (UniProtKB | ChEBI)
Binding site162substrate
Binding site164NADP+ (UniProtKB | ChEBI)
Binding site178substrate
Binding site190NADP+ (UniProtKB | ChEBI)
Binding site194NADP+ (UniProtKB | ChEBI)
Binding site198substrate
Binding site201substrate
Binding site289substrate
Binding site291-297NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function5-amino-6-(5-phosphoribosylamino)uracil reductase activity
Molecular Functiondiaminohydroxyphosphoribosylaminopyrimidine deaminase activity
Molecular FunctionNADP binding
Molecular Functionzinc ion binding
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Riboflavin biosynthesis protein RibD

Including 2 domains:

  • Recommended name
    Diaminohydroxyphosphoribosylaminopyrimidine deaminase
  • EC number
  • Short names
    DRAP deaminase
  • Alternative names
    • Riboflavin-specific deaminase
  • Recommended name
    5-amino-6-(5-phosphoribosylamino)uracil reductase
  • EC number
  • Alternative names
    • HTP reductase

Gene names

    • Name
      ribD
    • ORF names
      I3V23_11795

Organism names

Accessions

  • Primary accession
    A0A7S9WI21

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-117CMP/dCMP-type deaminase

Sequence similarities

In the C-terminal section; belongs to the HTP reductase family.
In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    357
  • Mass (Da)
    37,076
  • Last updated
    2021-09-29 v1
  • Checksum
    4123B1AC07AD8FCA
MRAALTLGQRGQGRTWPNPAVGCLIVKDGLIIGRGVTAPSGRPHAETQALAQAGEGARGATAYVTLEPCNHHGQTPPCSMALIEAGVARVVIAQDDPDPRTAGQGIARLRDAGISVTTDIAAPEAAQAHAGFFMRVTRGRPLVHLKLATTLDGRIATASGESRWITGPEARRMTHVMRGCHDAVMIGAATARADDPDLTLRDIGSPHQPLRVILSRRLDLPRGGRLQASIAKAPLWLVHGQDAPHEACAYWGEAGAHLIPLAQSQGGHLELNAALQALGDAGLTSVFCEGGGALAAGLLSADLVDRLSVFSAGSLIGAEGKPALGALGISELAAAPRFSRLTHRVVGADILSQWLRV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP065161
EMBL· GenBank· DDBJ
QPI86820.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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