A0A7S7YLI8 · A0A7S7YLI8_9CRUS

  • Protein
    NADH-ubiquinone oxidoreductase chain 4
  • Gene
    ND4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Branchiopoda > Anostraca > Artemiidae > Artemia

Accessions

  • Primary accession
    A0A7S7YLI8

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-25Helical
Transmembrane32-50Helical
Transmembrane56-78Helical
Transmembrane85-105Helical
Transmembrane125-143Helical
Transmembrane155-176Helical
Transmembrane188-206Helical
Transmembrane213-235Helical
Transmembrane241-262Helical
Transmembrane269-288Helical
Transmembrane308-337Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain52-325NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    377
  • Mass (Da)
    42,885
  • Last updated
    2021-06-02 v1
  • Checksum
    C1DE83484958703B
MLEFHLGWGTILLTLSSGVFFLMIISLKPNWPLTYSVILLSLFILLWLTFTAQSFIGFYIFFECSLIPTVILILGWGYQPERLPASYYFLFYTLLSSLPLLFVIVTHTSIYSSSILQFWGDFSDSMIFLLVILPFLVKLPIYFTHIWLPSAHVEAPVTGSMVLAAILLKLGGYGLYLVQGLNMHIETTVMSICMLGGIYSCLICLRQSDVKSLIAYSSVAHMSFVILATLMSGYYLNTSSILMMVSHGICSSGLFYLSYVFYTRIWSRSFLLTRSTTSLLPYLCFWWLGLSFFNMGLPPSANFFSEMYFFIGVFSLDWLMVALSGILCFFSSCYCIYLYSSTSHGESLYISSWLDYSLREYLISSAHFIPLLGIIFL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN240408
EMBL· GenBank· DDBJ
QPB69782.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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