A0A7S7RI22 · A0A7S7RI22_9VIRU
- ProteinInitiator protein NS1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids668 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Cofactor
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 212 | For nuclease activity | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | host cell nucleus | |
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Molecular Function | endonuclease activity | |
Molecular Function | helicase activity | |
Molecular Function | metal ion binding | |
Biological Process | DNA replication | |
Biological Process | symbiont-mediated arrest of host cell cycle during G2/M transition | |
Biological Process | symbiont-mediated perturbation of host apoptosis | |
Biological Process | symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint | |
Biological Process | viral DNA genome replication |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameInitiator protein NS1
- EC number
- Alternative names
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Monodnaviria > Shotokuvirae > Cossaviricota > Quintoviricetes > Piccovirales > Parvoviridae > Parvovirinae > Protoparvovirus
Accessions
- Primary accessionA0A7S7RI22
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, coiled coil, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 21-260 | PV NS1-Nuc | ||||
Sequence: AENEAFSFVFKCDNVQLNGKDVRWNNYTKPIQNEELTSLIRGAQTAMDQTEEEEMDWESEVDSLAKKQVQTFDALIKKCLFEVFVSKNIEPNECVWFIQHEWGKDQGWHCHVLLHSKNLQQATGKWLRRQMNMYWSRWLVTLCSVNLTPTEKIKLREIAEDSEWVTILTYRHKQTKKDYVKMVHFGNMIAYYFLTKKKIVHMTKESGYFLSTDSGWKFNFMKYQDRQIVSTLYTEQMKPE | ||||||
Coiled coil | 53-87 | |||||
Sequence: NEELTSLIRGAQTAMDQTEEEEMDWESEVDSLAKK | ||||||
Motif | 129-131 | RCR-2 | ||||
Sequence: HCH | ||||||
Motif | 212-216 | RCR-3 | ||||
Sequence: YFLTK | ||||||
Domain | 367-529 | SF3 helicase | ||||
Sequence: IFRMHGWNWIKVCHAIACVLNRQGGKRNTVLFHGPASTGKSIIAQAIAQAVGNVGCYNAANVNFPFNDCTNKNLIWIEEAGNFGQQVNQFKAICSGQTIRIDQKGKGSKQIEPTPVIMTTNENITIVRIGCEERPEHTQPIRDRMLNIKLVCKLPGDFGLVDK |
Sequence similarities
Belongs to the parvoviruses initiator protein NS1 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length668
- Mass (Da)76,749
- Last updated2021-06-02 v1
- Checksum1F73B563E786F542