A0A7S4XLL0 · A0A7S4XLL0_THAPI

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    A0A7S4XLL0

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane57-74Helical
Transmembrane86-104Helical
Transmembrane110-131Helical
Transmembrane143-162Helical
Transmembrane182-204Helical
Transmembrane216-235Helical
Transmembrane247-266Helical
Transmembrane273-295Helical
Transmembrane301-322Helical
Transmembrane334-356Helical
Transmembrane376-401Helical
Transmembrane422-445Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-103NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain107-390NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    446
  • Mass (Da)
    52,285
  • Last updated
    2021-06-02 v1
  • Checksum
    29DD787845D6B130
MMKFLMMMIFMMPLCFMKKMFWMVQMMLMLLMFLFMNLNLGILNFCNLSYMMSIDMMSYGLILLSIWIVILMLMSSENLLKSDYYVSFFLFNIIFLLIMLYMTFSMMNLFLFYLFFEGSLIPTLLLIVGWGYQPERIQAGMYLLFYTLFVSLPLLIGIFYIFNNLDFLVIYFLKFLNLNYYMLYFSMVMAFLVKMPMYFVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGLMRVIIFLQEINMKLNYIWIIISLVGGFYISLKCLCQVDIKSLIAYSSVAHMSLVIGGIMVMNYWGYMGSYMLMIGHGLCSSGMFCLANILYERLHSRSLFINSGMMSFMPSLSLWWFLLMSSNMAAPPSLNLMGEISLINSLLSWSWLSMLMLMMISFFSASYSLYLYSYIQHGNYYVGVYSYYTGVSREYLLLMLHWFPLNIMILSVDCGMIWF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH286070
EMBL· GenBank· DDBJ
QAV59284.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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