A0A7S2FP04 · A0A7S2FP04_9DINO

Function

function

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentCOPI vesicle coat
Cellular ComponentGolgi membrane
Molecular Functionstructural molecule activity
Biological Processendoplasmic reticulum to Golgi vesicle-mediated transport
Biological Processintra-Golgi vesicle-mediated transport
Biological Processintracellular protein transport
Biological Processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Coatomer subunit beta'

Gene names

    • ORF names
      AAND1436_LOCUS12781

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CCMP2222
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Dinophyceae > Gonyaulacales > Pyrocystaceae > Alexandrium

Accessions

  • Primary accession
    A0A7S2FP04

Subcellular Location

Cytoplasmic vesicle, COPI-coated vesicle membrane
; Peripheral membrane protein
Golgi apparatus membrane
; Peripheral membrane protein
Membrane
; Peripheral membrane protein
Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.

Keywords

Interaction

Subunit

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.

Family & Domains

Features

Showing features for repeat, domain, region, compositional bias.

TypeIDPosition(s)Description
Repeat1-33WD
Repeat44-86WD
Repeat89-132WD
Repeat133-164WD
Domain227-680Coatomer WD associated region
Region778-821Disordered
Compositional bias781-821Pro residues
Region850-888Disordered

Sequence similarities

Belongs to the WD repeat COPB2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    888
  • Mass (Da)
    96,174
  • Last updated
    2021-06-02 v1
  • Checksum
    CD353D267F73AED1
MEAHTDYIRYLAVHPNMPYLLTSSDDMTIKLWDWEKNWQMSQVFEGHAHYVMMAQWNPKDNTIFASCSLDRSIKVWGVTGGNAAAHFTLTGHQRGVNCIEYAAGGEKPYLISGSDDRTVKIWDYQTKHCIQTLTGHTNNVSASLFHPTLPIILTGSEDGTVRIWHGATYRLEATLNYFLERVWSIATLHGSNAAAIGYDEGTVVIKLGSEEPVASMHSGKVIFAKGNEIQTTNLKLVDEGVTPGDGERIPLTVKEMGAAEIFPQYISHHPNGRLFAVCGDGEFVIYTAQALRNKSFGQALEFVWGHSGAYATRDNAGSGKITVFQDFKESFSFKPPFVVDELYGGRLIGVRGGDFICFYDWAEYRLIRRIDVVPKLVIWSEDGTNLVLATADSFYVLRHDRDAVTAANVGGATVDEDGIEAAFELLSEVTDKVVSGTWVGDCFVYVSHAQRLICLVAGHQETIAHLDRPQYLLGYMPDQSKLYLIDKEYSITSWPLHLALVEYQSAVMRKDLAAAEKFFDQLPESLHNRVARFLENQGHVQEALQVSKDDEHRFELATQLGKLQMAADIIVSISSQASPAMPPRNKWKSLGDVALEQGDFALARRCFREARDIGSLFLLATSCGDVEELRSAGKMASEGGITNVACLCALLQGDAKGALQVLVKASRLPEAAFFARTYCPSELPQVVKLWKADLSQVNQAVADSLADPVQYPDLFPDFELTLAAEQAFQARNERCPPMAASYPEEKERLGMDVLEQIKALSPEGFRASMLGGAVAAAPAPAPAPAVAPAPAPAAAPAPAPVPTPAPPVAAPAAQPAPPPETVVEAVPAGPEVTPMPSPEGLVPEAAAPLLDPEFSRPPEAAVPPELAPQGADEGAAGGGASAPLLDLL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias781-821Pro residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HBGQ01025948
EMBL· GenBank· DDBJ
CAD9404594.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

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