A0A7S2E019 · A0A7S2E019_9DINO
- ProteinDNA polymerase epsilon catalytic subunit
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids198 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
DNA polymerase II participates in chromosomal DNA replication.
Catalytic activity
- a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | epsilon DNA polymerase complex | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | metal ion binding | |
Molecular Function | single-stranded DNA 3'-5' DNA exonuclease activity | |
Biological Process | base-excision repair, gap-filling | |
Biological Process | DNA replication proofreading | |
Biological Process | leading strand elongation | |
Biological Process | mitotic cell cycle | |
Biological Process | nucleotide-excision repair, DNA gap filling |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase epsilon catalytic subunit
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Dinophyceae > Gonyaulacales > Pyrocystaceae > Alexandrium
Accessions
- Primary accessionA0A7S2E019
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 56-197 | DNA-directed DNA polymerase family B exonuclease | ||||
Sequence: LYEYDVNYMNRVCIDNCINCGKWFQVLRNQMATSVDDIWDTQCTLTAKDEMLAKPGLRIFAWDIECTKEPLKFPDSAHDRITLISVMVDGSGFLIVNRAEVSADIEPLEYTPKPEYEGLFSTYNEADEAALIRRFFQLIRDT |
Sequence similarities
Belongs to the DNA polymerase type-B family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length198
- Mass (Da)22,594
- Last updated2021-06-02 v1
- Checksum5E09AF6F3030FF92
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: R | ||||||
Non-terminal residue | 198 | |||||
Sequence: S |