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A0A7R9PK32 · A0A7R9PK32_TIMGE

Function

function

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Note: Binds 1 divalent metal cation per subunit.

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionacyltransferase activity, transferring groups other than amino-acyl groups
Molecular Functionmetal ion binding
Biological ProcesstRNA threonylcarbamoyladenosine modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    N(6)-L-threonylcarbamoyladenine synthase
  • EC number

Gene names

    • ORF names
      TGEB3V08_LOCUS3522

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Polyneoptera > Phasmatodea > Timematodea > Timematoidea > Timematidae > Timema

Accessions

  • Primary accession
    A0A7R9PK32

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-19
ChainPRO_503078943320-442N6-L-threonylcarbamoyladenine synthase

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain64-388Gcp-like

Sequence similarities

Belongs to the KAE1 / TsaD family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    442
  • Mass (Da)
    48,347
  • Last updated
    2021-06-02 v1
  • MD5 Checksum
    423177A24403B6ABF4E4343A0121B3A7
MKQVVCILKLLFFPKMIPALLYRIVRSCYIKRNMCTPVNHKSVILGLETSCDDTGCAIVDSCGNILGEALHSQLQVHLNNGGIIPPIARDLHKQHIERVVEEALASANLGLGDVDAIATTVKPGMALSLLVGMNHGKHLAKTWGKPFIPIHHMEAHALTIRMVTQVEFPFLVLLISGGHCLLAVAQGVHQFLLLGQSLDDAPGEAFDKTARRMKLHSLPEFRGLSGGAAIQLAATRGDPLSFQFPFMLSGYRDCNFSMAGLKNKARQHILRQEHEHGVEGDGIIPGVYDLCASVQWGITSHLCQRLQRAMEFISMRDMLPLDRRTLVRHCRHKVGTSTGESLSKVVSGGVACNSFITGALGVVCEEYGYSLAVPPPKLCTDNGVMIAWNGVEKWRSGVGVVPDLDAIDIEPECPLGVDRREDVVNANIKCKWIKPRALLRIG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
OE840130
EMBL· GenBank· DDBJ
CAD7589593.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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