A0A7R7ZLN0 · A0A7R7ZLN0_ASPCH

Function

function

Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Lipid metabolism.
Phospholipid metabolism; phosphatidylcholine biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site95-97S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site177-178S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Cellular Componentmitochondrial membrane
Molecular Functionphosphatidyl-N-methylethanolamine N-methyltransferase activity
Biological Processmethylation
Biological Processphosphatidylcholine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphatidyl-N-methylethanolamine N-methyltransferase
  • EC number
  • Alternative names
    • Phospholipid methyltransferase
      (PLMT
      )

Gene names

    • Name
      OPI3
    • ORF names
      ACHE_30977A

Organism names

  • Taxonomic identifier
  • Strain
    • M1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Aspergillus

Accessions

  • Primary accession
    A0A7R7ZLN0

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, intramembrane, transmembrane.

TypeIDPosition(s)Description
Topological domain1-12Lumenal
Intramembrane13-33Helical
Transmembrane13-33Helical
Topological domain34-45Lumenal
Transmembrane45-66Helical
Transmembrane86-108Helical
Topological domain112-154Lumenal
Transmembrane115-132Helical
Transmembrane152-173Helical
Topological domain176-200Cytoplasmic

Keywords

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    200
  • Mass (Da)
    22,292
  • Last updated
    2021-06-02 v1
  • Checksum
    24F6A504BEF259DA
MAALTDFVDFSQLSLQVTALSIAFNPIFWNIVARTEYRNHFLTRIFGSPYYGCYFLAFTIFSLGILRDHLYQLALADQPYYAPVHQPILGAVLFGVGSVLVLSSMYALGVTGTYLGDYFGILMDAPVTGFPFNVTGSPMYWGSTLNFLGVALYHGKVAGIALTAEVFILYWFALQWEDPFTAGIYAKRERERAKQAGKSQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP024418
EMBL· GenBank· DDBJ
BCR86990.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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