A0A7R7VDK2 · A0A7R7VDK2_ASPCH

Function

Catalytic activity

  • Hydrolysis of proteins with broad specificity, and of Bz-Arg-OEt > Ac-Tyr-OEt. Does not hydrolyze peptide amides.
    EC:3.4.21.63 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

144450100150200250300350400
TypeIDPosition(s)Description
Active site164Charge relay system
Active site196Charge relay system
Active site352Charge relay system

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular Functionserine-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alkaline protease 1
  • EC number
  • Alternative names
    • Aspergillopeptidase B
    • Aspergillus proteinase B
    • Elastase
    • Elastinolytic serine proteinase
    • Oryzin

Gene names

    • Name
      ALP1
    • ORF names
      ACHE_10233S

Organism names

  • Taxonomic identifier
  • Strain
    • M1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Aspergillus

Accessions

  • Primary accession
    A0A7R7VDK2

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_503117541521-444Alkaline protease 1

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain37-122Inhibitor I9
Domain162-394Peptidase S8/S53
Region400-430Disordered

Sequence similarities

Belongs to the peptidase S8 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    444
  • Mass (Da)
    47,936
  • Last updated
    2021-06-02 v1
  • Checksum
    F2C494E8A1E97205
MQFFKRALLLFGALLPAALGHPMVQGRHRSPEMIPGRYIVTFKHGLDTAKVDAHTAWATDLHKRHLEQRDQTNDASMPIGIQKSYRFTSFSAYYGSFDDATIEEIRKHEDVEYVEQDQIWYLDATISQNNAPWGLGSISHRGQPSTTYVYDDSAGEGTFGYVVDTGINVDHREFGGRASLAYNAVDNSDHVDTVGHGTHVAGTIGGATFGVAKKANLLSVKVFAGESGRTSDILDGFNWAANDIATKRRTGKAAINMSLGGGFSFAFNRAVENAYDSGVLSIVAAGNENMDARFTSPASAENAFTVAAIDRNNSRASFSNYGSVVDIFAPGVNILSSWIGNDTATNTISGTSMATPHVVGLAIYVMGLENLADANAVSKRLKELGTRDVVTRTSGSPNLLAFNGAQGGAGTGSGDGHGRVDEDDEDEDENWDWPFEMKRAVRRW

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP024416
EMBL· GenBank· DDBJ
BCR82831.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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