A0A7R6PBU7 · A0A7R6PBU7_9GAMM

Function

function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site23-27substrate
Binding site73substrate
Site73Transition state stabilizer
Binding site150substrate
Binding site205substrate
Binding site323substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionuroporphyrinogen decarboxylase activity
Biological Processprotoporphyrinogen IX biosynthetic process from glutamate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uroporphyrinogen decarboxylase
  • EC number
  • Short names
    UPD
    ; URO-D

Gene names

    • Name
      hemE
    • ORF names
      CVPH_1484

Organism names

Accessions

  • Primary accession
    A0A7R6PBU7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain18-27Uroporphyrinogen decarboxylase (URO-D)
Domain138-154Uroporphyrinogen decarboxylase (URO-D)

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    347
  • Mass (Da)
    38,495
  • Last updated
    2021-09-29 v1
  • Checksum
    F9CEF3A085F26BEE
MSFDYINALLKKPTSRTPIWVMRQAGRYLPEYRVTRKQAGDFLSLCKNPELACEVTMQPIDRFDLDAAILFSDILTIPDAMGLGLYFSEGEGPKFSNPLNTLASIEQLKKPNVGNELSYVTDAVSVIKKALNNKVPLIGFTGSPWTLATYMVEGGSSKNFAKVKGLMYENPAHMHQLLDKLADTIIDYLNGQIQAGADSVMIFDTWGGLLNKQSYEDFSLQYMAKIVNGIKREFNGKIIPVTLFTKGGAMRLEQIANSGCDGVALDWTVELNDAQRRIGAKVTLQGNLDPCVLYASPEKIRKEVKKILSQFQGNTGHVFNLGHGISPDVNPEHMKILVDAVHEFSKR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP012977
EMBL· GenBank· DDBJ
BBB23322.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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