A0A7P0TAY2 · A0A7P0TAY2_HUMAN

  • Protein
    Heat shock protein 90 beta family member 1
  • Gene
    HSP90B1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Features

Showing features for binding site.

166150100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site103ATP (UniProtKB | ChEBI)
Binding site107ATP (UniProtKB | ChEBI)
Binding site149ATP (UniProtKB | ChEBI)
Binding site154ATP (UniProtKB | ChEBI)
Binding site162ATP (UniProtKB | ChEBI)
Binding site168ATP (UniProtKB | ChEBI)
Binding site169-170ATP (UniProtKB | ChEBI)
Binding site194-199ATP (UniProtKB | ChEBI)
Binding site245ATP (UniProtKB | ChEBI)
Binding site448ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent protein folding chaperone
Molecular Functionunfolded protein binding

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Heat shock protein 90 beta family member 1

Gene names

    • Name
      HSP90B1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A7P0TAY2

Proteomes

Organism-specific databases

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 446 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for signal, chain, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Signal1-21UniProt
ChainPRO_503137614822-661UniProt
Modified residue (large scale data)42PRIDEPhosphoserine
Modified residue (large scale data)44PRIDEPhosphothreonine
Modified residue (large scale data)64PRIDEPhosphoserine
Modified residue (large scale data)106PRIDEPhosphoserine
Modified residue (large scale data)109PRIDEPhosphoserine
Modified residue (large scale data)155PRIDEPhosphothreonine
Modified residue (large scale data)169PRIDEPhosphoserine
Modified residue (large scale data)172PRIDEPhosphoserine
Modified residue (large scale data)306PRIDEPhosphoserine
Modified residue (large scale data)403PRIDEPhosphoserine
Modified residue (large scale data)439PRIDEPhosphoserine
Modified residue (large scale data)447PRIDEPhosphoserine
Modified residue (large scale data)501PRIDEPhosphoserine
Modified residue (large scale data)504PRIDEPhosphothreonine

Proteomic databases

Expression

Gene expression databases

    • ENSG00000166598Expressed in right lobe of thyroid gland and 212 other cell types or tissues

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain96-255Histidine kinase/HSP90-like ATPase
Region288-323Disordered
Compositional bias290-314Acidic residues

Sequence similarities

Belongs to the heat shock protein 90 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    661
  • Mass (Da)
    76,369
  • Last updated
    2021-06-02 v1
  • Checksum
    98F745DE14203754
MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKVLWKLQIVEILVSAFKRKLFCEQIKLQLVTL

Computationally mapped potential isoform sequences

There are 16 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P14625ENPL_HUMANHSP90B1803
H0YIV0H0YIV0_HUMANHSP90B1796
A0A7P0T8C8A0A7P0T8C8_HUMANHSP90B159
A0A7P0T917A0A7P0T917_HUMANHSP90B1719
A0A7P0T8R3A0A7P0T8R3_HUMANHSP90B1251
A0A7P0T823A0A7P0T823_HUMANHSP90B1813
A0A7P0T885A0A7P0T885_HUMANHSP90B1274
F8W026F8W026_HUMANHSP90B148
A0A7P0TAT8A0A7P0TAT8_HUMANHSP90B1814
A0A7P0TBC2A0A7P0TBC2_HUMANHSP90B1465
A0A7P0TAC2A0A7P0TAC2_HUMANHSP90B155
A0A7P0TAE1A0A7P0TAE1_HUMANHSP90B1789
A0A7P0TAG4A0A7P0TAG4_HUMANHSP90B153
A0A7P0Z405A0A7P0Z405_HUMANHSP90B1163
A0A7P0Z4B4A0A7P0Z4B4_HUMANHSP90B168
A0A087WT78A0A087WT78_HUMANHSP90B1751

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias290-314Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC078819
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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