A0A7P0TAW3 · A0A7P0TAW3_HUMAN
- ProteinTransitional endoplasmic reticulum ATPase
- GeneVCP
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids772 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | endoplasmic reticulum | |
Cellular Component | nucleoplasm | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | lipid binding | |
Molecular Function | protein-containing complex binding | |
Biological Process | autophagy | |
Biological Process | cellular response to stress |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTransitional endoplasmic reticulum ATPase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A7P0TAW3
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 346 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | ||
---|---|---|---|---|---|---|
Modified residue (large scale data) | 3 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 7 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 13 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 37 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 197 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 282 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 284 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 326 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 352 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 416 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 702 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 705 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 765 | PRIDE | Phosphoserine | |||
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 25-108 | CDC48 N-terminal subdomain | |||
Domain | 125-191 | CDC48 | |||
Domain | 237-373 | AAA+ ATPase | |||
Domain | 510-649 | AAA+ ATPase | |||
Region | 708-727 | Disordered | |||
Sequence similarities
Belongs to the AAA ATPase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length772
- Mass (Da)86,119
- Last updated2021-06-02 v1
- Checksum396605497BEA6E10
Computationally mapped potential isoform sequences
There are 21 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P55072 | TERA_HUMAN | VCP | 806 | ||
C9JUP7 | C9JUP7_HUMAN | VCP | 761 | ||
A0A7P0T9X5 | A0A7P0T9X5_HUMAN | VCP | 110 | ||
A0A7P0T8D3 | A0A7P0T8D3_HUMAN | VCP | 47 | ||
A0A7P0T8D6 | A0A7P0T8D6_HUMAN | VCP | 50 | ||
A0A7P0T8Q4 | A0A7P0T8Q4_HUMAN | VCP | 77 | ||
A0A7P0T8Q5 | A0A7P0T8Q5_HUMAN | VCP | 754 | ||
A0A7P0T946 | A0A7P0T946_HUMAN | VCP | 77 | ||
A0A7P0T971 | A0A7P0T971_HUMAN | VCP | 55 | ||
A0A7P0T8A3 | A0A7P0T8A3_HUMAN | VCP | 760 | ||
A0A7P0TAY0 | A0A7P0TAY0_HUMAN | VCP | 237 | ||
A0A7P0TBF1 | A0A7P0TBF1_HUMAN | VCP | 56 | ||
A0A7P0TBK7 | A0A7P0TBK7_HUMAN | VCP | 107 | ||
A0A7P0TAQ1 | A0A7P0TAQ1_HUMAN | VCP | 733 | ||
A0A7P0TA22 | A0A7P0TA22_HUMAN | VCP | 76 | ||
A0A7P0Z4C6 | A0A7P0Z4C6_HUMAN | VCP | 694 | ||
A0A7P0Z4D1 | A0A7P0Z4D1_HUMAN | VCP | 102 | ||
A0A7I2YQJ0 | A0A7I2YQJ0_HUMAN | VCP | 43 | ||
A0A7I2V2Y2 | A0A7I2V2Y2_HUMAN | VCP | 458 | ||
A0A7I2V540 | A0A7I2V540_HUMAN | VCP | 804 | ||
A0A7I2V5G8 | A0A7I2V5G8_HUMAN | VCP | 334 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL353795 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |