A0A7P0T936 · A0A7P0T936_HUMAN

  • Protein
    Microtubule-associated protein
  • Gene
    MAPT
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxon
Cellular Componentcytosol
Cellular Componentdendrite
Cellular Componentmicrotubule
Cellular Componentplasma membrane
Molecular Functionmicrotubule binding

Names & Taxonomy

Protein names

  • Recommended name
    Microtubule-associated protein

Gene names

    • Name
      MAPT

Organism names

Accessions

  • Primary accession
    A0A7P0T936

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cell projection, axon
Cell projection, dendrite
Cytoplasm, cytoskeleton
Cytoplasm, cytosol
Membrane
; Peripheral membrane protein

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 363 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)53PRIDEPhosphothreonine
Modified residue (large scale data)55PRIDEPhosphoserine
Modified residue (large scale data)117PRIDEPhosphothreonine
Modified residue (large scale data)123PRIDEPhosphothreonine
Modified residue (large scale data)126PRIDEPhosphoserine
Modified residue (large scale data)133PRIDEPhosphoserine
Modified residue (large scale data)137PRIDEPhosphoserine
Modified residue (large scale data)139PRIDEPhosphotyrosine
Modified residue (large scale data)140PRIDEPhosphoserine
Modified residue (large scale data)141PRIDEPhosphoserine
Modified residue (large scale data)144PRIDEPhosphoserine
Modified residue (large scale data)147PRIDEPhosphothreonine
Modified residue (large scale data)152PRIDEPhosphoserine
Modified residue (large scale data)154PRIDEPhosphothreonine
Modified residue (large scale data)156PRIDEPhosphoserine
Modified residue (large scale data)159PRIDEPhosphothreonine
Modified residue (large scale data)173PRIDEPhosphothreonine
Modified residue (large scale data)177PRIDEPhosphoserine
Modified residue (large scale data)179PRIDEPhosphoserine
Modified residue (large scale data)180PRIDEPhosphoserine
Modified residue (large scale data)204PRIDEPhosphoserine
Modified residue (large scale data)205PRIDEPhosphothreonine
Modified residue (large scale data)227PRIDEPhosphoserine
Modified residue (large scale data)231PRIDEPhosphoserine
Modified residue (large scale data)339PRIDEPhosphoserine
Modified residue (large scale data)377PRIDEPhosphotyrosine
Modified residue (large scale data)379PRIDEPhosphoserine
Modified residue (large scale data)383PRIDEPhosphoserine
Modified residue (large scale data)386PRIDEPhosphothreonine
Modified residue (large scale data)387PRIDEPhosphoserine
Modified residue (large scale data)392PRIDEPhosphoserine
Modified residue (large scale data)395PRIDEPhosphoserine
Modified residue (large scale data)396PRIDEPhosphoserine
Modified residue (large scale data)397PRIDEPhosphothreonine
Modified residue (large scale data)399PRIDEPhosphoserine
Modified residue (large scale data)405PRIDEPhosphoserine

Keywords

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias1-20Basic and acidic residues
Region1-197Disordered
Compositional bias27-45Basic and acidic residues
Compositional bias74-90Basic and acidic residues
Compositional bias133-153Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    424
  • Mass (Da)
    44,165
  • Last updated
    2021-06-02 v1
  • Checksum
    F220FCE2BE778ED5
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPDGVVLSLPRLECNGTISAHCNLHLLDSSNSPVSASQVAGITGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P10636TAU_HUMANMAPT758
A0A0G2JQJ7A0A0G2JQJ7_HUMANMAPT758
A0A0G2JS76A0A0G2JS76_HUMANMAPT776
A0A0G2JPD5A0A0G2JPD5_HUMANMAPT758
A0A0G2JMX7A0A0G2JMX7_HUMANMAPT776
A0A7I2PJZ2A0A7I2PJZ2_HUMANMAPT833
A0A7I2PLE3A0A7I2PLE3_HUMANMAPT736
I3L2Z2I3L2Z2_HUMANMAPT59
I3L170I3L170_HUMANMAPT341

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-20Basic and acidic residues
Compositional bias27-45Basic and acidic residues
Compositional bias74-90Basic and acidic residues
Compositional bias133-153Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC217771
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CR936218
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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