A0A7N4FLU7 · A0A7N4FLU7_MOUSE
- Proteinnon-specific serine/threonine protein kinase
- GeneBraf
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids750 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A7N4FLU7
Proteomes
Organism-specific databases
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-21 | Disordered | ||||
Sequence: QALFNGDMEPEAGAGAAASSA | ||||||
Domain | 138-210 | RBD | ||||
Sequence: PIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVL | ||||||
Domain | 217-263 | Phorbol-ester/DAG-type | ||||
Sequence: THNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMC | ||||||
Region | 287-439 | Disordered | ||||
Sequence: EASFPETALPSGSSSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSSSEDRSRMKTLGRRDSSDDWEIPDG | ||||||
Compositional bias | 292-319 | Polar residues | ||||
Sequence: ETALPSGSSSAPPSDSTGPQILTSPSPS | ||||||
Compositional bias | 374-410 | Polar residues | ||||
Sequence: GGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKS | ||||||
Compositional bias | 411-435 | Basic and acidic residues | ||||
Sequence: SSSSSSEDRSRMKTLGRRDSSDDWE | ||||||
Domain | 441-701 | Protein kinase | ||||
Sequence: ITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELL |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length750
- Mass (Da)83,202
- Last updated2021-04-07 v1
- Checksum80E541F030A8F56A
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P28028 | BRAF_MOUSE | Braf | 751 |
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: Q | ||||||
Compositional bias | 292-319 | Polar residues | ||||
Sequence: ETALPSGSSSAPPSDSTGPQILTSPSPS | ||||||
Compositional bias | 374-410 | Polar residues | ||||
Sequence: GGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKS | ||||||
Compositional bias | 411-435 | Basic and acidic residues | ||||
Sequence: SSSSSSEDRSRMKTLGRRDSSDDWE |
Keywords
- Technical term