A0A7M4FDN5 · A0A7M4FDN5_CROPO
- Protein2-(3-amino-3-carboxypropyl)histidine synthase subunit 1
- GeneDPH1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids394 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H+
Cofactor
Pathway
Protein modification; peptidyl-diphthamide biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-(3-amino-3-carboxypropyl)histidine synthase activity | |
Molecular Function | iron-sulfur cluster binding | |
Molecular Function | metal ion binding | |
Biological Process | protein histidyl modification to diphthamide |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-(3-amino-3-carboxypropyl)histidine synthase subunit 1
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Crocodylia > Longirostres > Crocodylidae > Crocodylus
Accessions
- Primary accessionA0A7M4FDN5
Proteomes
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 313-328 | Polar residues | |||
Region | 313-394 | Disordered | |||
Compositional bias | 367-382 | Polar residues | |||
Sequence similarities
Belongs to the DPH1/DPH2 family. DPH1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length394
- Mass (Da)43,422
- Last updated2021-04-07 v1
- ChecksumCB6BF524DD5E4156
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A7M4G1I2 | A0A7M4G1I2_CROPO | DPH1 | 510 | ||
A0A7M4FER6 | A0A7M4FER6_CROPO | DPH1 | 450 | ||
A0A7M4FH26 | A0A7M4FH26_CROPO | DPH1 | 399 | ||
A0A7M4FCA5 | A0A7M4FCA5_CROPO | DPH1 | 452 | ||
A0A7M4FC87 | A0A7M4FC87_CROPO | DPH1 | 430 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 313-328 | Polar residues | |||
Compositional bias | 367-382 | Polar residues | |||
Keywords
- Technical term