A0A7M2JGR7 · A0A7M2JGR7_PSEFL

  • Protein
    3-phosphoshikimate 1-carboxyvinyltransferase
  • Gene
    aroA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site3223-phosphoshikimate (UniProtKB | ChEBI)
Binding site322phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site3233-phosphoshikimate (UniProtKB | ChEBI)
Binding site3273-phosphoshikimate (UniProtKB | ChEBI)
Binding site395phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site423phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site4683-phosphoshikimate (UniProtKB | ChEBI)
Binding site4703-phosphoshikimate (UniProtKB | ChEBI)
Binding site470phosphoenolpyruvate (UniProtKB | ChEBI)
Active site616Proton acceptor
Binding site6163-phosphoshikimate (UniProtKB | ChEBI)
Binding site6433-phosphoshikimate (UniProtKB | ChEBI)
Binding site647phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site688phosphoenolpyruvate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-phosphoshikimate 1-carboxyvinyltransferase activity
Molecular FunctionNAD+ binding
Molecular Functionprephenate dehydrogenase (NAD+) activity
Molecular Functionprephenate dehydrogenase (NADP+) activity
Biological Processchorismate biosynthetic process
Biological Processtyrosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-phosphoshikimate 1-carboxyvinyltransferase
  • EC number
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate synthase
      (EPSP synthase
      ; EPSPS
      )

Gene names

    • Name
      aroA
    • ORF names
      IM720_09630

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KF1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A7M2JGR7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-291Prephenate/arogenate dehydrogenase

Sequence similarities

Belongs to the EPSP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    736
  • Mass (Da)
    77,942
  • Last updated
    2021-06-02 v1
  • Checksum
    819FC7D18D41BF51
MIGRLVVVGLGLIGGSFAKGLRESGLCGEVVGVDLDPQSRKLAVELGVVDRCEADLALACQGADVIQLAVPILAMEKLLALLAGMDLGQAILTDVGSAKGNVVRAAQQAFGGMPSRFVPGHPIAGSEQSGVEASNAQLFRRHKVILTPLEQTDPAALAVVDRLWRELGADVEHMQVERHDEVLAATSHLPHLLAFGLVDSLAKRNENLEIFRYAAGGFRDFTRIAGSDPVMWHDIFLANREAVLRTLDTFRSDLDALRDAVDAGDGHQLLGVFTRARVAREHFSKILARRAYMETAVNADDLTFIANPGGRLSGRIRVPGDKSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEGPHHGRVTIHGVGLHGLKPAPGPIYLGNSGTSMRLLSGLLAAQRFDSVLTGDASLSKRPMNRVAKPLRDMGAVIETGPEGRPPLTIRGGQTLKGLAYAMPMASAQVKSCLLLAGLYAEGKTSVTEPAPTRDHTERMLRGFGYPVVVEGATASVESGHGLTAAHIEVPGDISSSAFFLVAASIAEGSELLLEHVGINPTRTGVIDILRLMGADISLENQREVGGEPVADLRVRAAVLKGIEIPEALVPLAIDEFPVLFVAAACATGRTVLRGAEELRVKESDRIQVMADGLLALGVKCEPTPDGIIIEGGPMGGGEVHAHGDHRIAMAFSVASLRATAPIRIRDCDNVATSFPNFLTLCAQVGIRVAQEAQL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP063233
EMBL· GenBank· DDBJ
QOU08170.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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