A0A7L8ACX7 · A0A7L8ACX7_9FLAO

  • Protein
    DNA polymerase IV
  • Gene
    dinB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Features

Showing features for binding site, site, active site.

136550100150200250300350
Type
IDPosition(s)Description
Binding site14Mg2+ (UniProtKB | ChEBI)
Site19Substrate discrimination
Binding site108Mg2+ (UniProtKB | ChEBI)
Active site109

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiondamaged DNA binding
Molecular FunctionDNA-directed DNA polymerase activity
Molecular Functionmagnesium ion binding
Biological ProcessDNA-templated DNA replication
Biological Processerror-prone translesion synthesis
Biological ProcessSOS response

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA polymerase IV
  • EC number
  • Short names
    Pol IV

Gene names

    • Name
      dinB
    • ORF names
      H9I45_10430

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KCTC 52418
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae

Accessions

  • Primary accession
    A0A7L8ACX7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-190UmuC

Sequence similarities

Belongs to the DNA polymerase type-Y family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    365
  • Mass (Da)
    41,637
  • Last updated
    2021-09-29 v1
  • Checksum
    9A25E69F0D2B1F70
MELQPPFRKIIHVDMDAFYASVAQLDNPELRGKAIAVGGNEIRGVVSAASYEARKFGVKSAMSGFMAKKKCPHLIFVKSDFERYKELSAKIREIFYEYTDLVEPLSLDEAYLDVTENKKGNTSANDIAREIRARIFEVTGLRASAGISINKFIAKVASDINKPNGQKTVHPEEVIKFLEELPVNKFYGVGKVTAAKMYNLGIFVGNDLKKKSLEELVTLFGKSGTHYYNIVRGIHNSAVKPNRIRKSLAAERTFNENISSEIYMIEKLEKIADELERRMLKNDTKGKTITLKIKYSDFTQQTRSKTKPHFMQTKKEFFPVVKELLFQDKLVNSVRLLGLSFGNLNTEIKEPVWVQLKFDFNTHRF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP061813
EMBL· GenBank· DDBJ
QOD59767.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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