A0A7L8ACK1 · A0A7L8ACK1_9FLAO
- ProteinMethionine--tRNA ligase
- GenemetG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids684 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Catalytic activity
- tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 146 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 149 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 159 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 162 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 338 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | methionine-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Biological Process | methionyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae
Accessions
- Primary accessionA0A7L8ACK1
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for motif, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 14-24 | 'HIGH' region | |||
Motif | 335-339 | 'KMSKS' region | |||
Domain | 583-684 | TRNA-binding | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length684
- Mass (Da)77,581
- Last updated2021-09-29 v1
- ChecksumF7B1DEBBCE45070D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP061813 EMBL· GenBank· DDBJ | QOD59726.1 EMBL· GenBank· DDBJ | Genomic DNA |